On November 25 launch of the book entitled “Muscarinic Receptor: From Structure to Animal Models”, whose editors are dr. Jan Jakubík from Department of Neurochemistry Institute of Physiology CAS and prof. Jaromír Mysliveček from Institute of Physiology 1st Faculty of Medicine, was held at the Academic Club of the 1st Faculty of Medicine UK. This book is a part of prestigious series of Neuromethods, publised by a major publishing house Springer. The book includes a basic description of the muscarinic receptors using crystallographic studies, binding studies, autoradiography and PET imaging. It also deals with the study of allosteric modulation of muscarinic receptors and examples of mice models with knockout genes for muscarinic receptors and demonstrates their use in the study of the physiology and behavior. During the first 3 months, the electronic version of the book has been downloaded over 2000-times.