{"id":24956,"date":"2024-07-10T16:55:15","date_gmt":"2024-07-10T14:55:15","guid":{"rendered":"https:\/\/fgu.antstudio.dev\/research-and-laboratories\/research-departments\/translacni-metabolismus\/"},"modified":"2025-12-29T12:20:16","modified_gmt":"2025-12-29T11:20:16","slug":"laboratory-of-translational-metabolism","status":"publish","type":"page","link":"https:\/\/fgu.cas.cz\/en\/research-and-laboratories\/research-departments\/laboratory-of-translational-metabolism\/","title":{"rendered":"Laboratory of Translational Metabolism"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"24956\" class=\"elementor elementor-24956 elementor-1494\" data-elementor-post-type=\"page\">\n\t\t\t\t<div class=\"elementor-element elementor-element-22f0716 e-flex e-con-boxed e-con e-parent\" data-id=\"22f0716\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-2f4f528 e-con-full elementor-hidden-tablet elementor-hidden-mobile e-flex e-con e-child\" data-id=\"2f4f528\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-ad6ff43 elementor-widget__width-initial elementor-widget elementor-widget-heading\" data-id=\"ad6ff43\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h1 class=\"elementor-heading-title elementor-size-default\">Laboratory of Translational Metabolism<\/h1>\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-3306453 e-flex e-con-boxed e-con e-parent\" data-id=\"3306453\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-6f2ab90 elementor-absolute elementor-hidden-tablet elementor-hidden-mobile elementor-widget elementor-widget-image\" data-id=\"6f2ab90\" data-element_type=\"widget\" data-settings=\"{&quot;_position&quot;:&quot;absolute&quot;}\" data-widget_type=\"image.default\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"708\" height=\"789\" src=\"https:\/\/fgu.cas.cz\/wp-content\/uploads\/2025\/11\/bg-3.webp\" class=\"attachment-large size-large wp-image-51089\" alt=\"-\" srcset=\"https:\/\/fgu.cas.cz\/wp-content\/uploads\/2025\/11\/bg-3.webp 708w, https:\/\/fgu.cas.cz\/wp-content\/uploads\/2025\/11\/bg-3-269x300.webp 269w\" sizes=\"(max-width: 708px) 100vw, 708px\" title=\"\">\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-62ed919 e-con-full elementor-hidden-tablet elementor-hidden-mobile e-flex e-con e-child\" data-id=\"62ed919\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;,&quot;sticky&quot;:&quot;top&quot;,&quot;sticky_on&quot;:[&quot;desktop&quot;],&quot;sticky_offset&quot;:80,&quot;sticky_parent&quot;:&quot;yes&quot;,&quot;sticky_effects_offset&quot;:0,&quot;sticky_anchor_link_offset&quot;:0}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-50924c1 elementor-widget elementor-widget-heading\" data-id=\"50924c1\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">Content of this page<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-8d206bc elementor-toc--content-ellipsis elementor-widget elementor-widget-table-of-contents\" data-id=\"8d206bc\" data-element_type=\"widget\" data-settings=\"{&quot;headings_by_tags&quot;:[&quot;h2&quot;],&quot;exclude_headings_by_selector&quot;:[],&quot;marker_view&quot;:&quot;bullets&quot;,&quot;icon&quot;:{&quot;value&quot;:&quot;&quot;,&quot;library&quot;:&quot;&quot;},&quot;min_height&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:200,&quot;sizes&quot;:[]},&quot;no_headings_message&quot;:&quot;No headings were found on this page.&quot;,&quot;min_height_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;min_height_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]}}\" data-widget_type=\"table-of-contents.default\">\n\t\t\t\t\t\t\t\t\t<div id=\"elementor-toc__8d206bc\" class=\"elementor-toc__body\">\n\t\t\t<div class=\"elementor-toc__spinner-container\">\n\t\t\t\t<i class=\"elementor-toc__spinner eicon-animation-spin eicon-loading\" aria-hidden=\"true\"><\/i>\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-3c81cea e-con-full e-flex e-con e-child\" data-id=\"3c81cea\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-a371a1f elementor-widget elementor-widget-image\" data-id=\"a371a1f\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"1000\" height=\"357\" src=\"https:\/\/fgu.cas.cz\/wp-content\/uploads\/2024\/07\/l7a51u878jdpoixdvn0j.png\" class=\"attachment-1536x1536 size-1536x1536 wp-image-1498\" alt=\"-\" srcset=\"https:\/\/fgu.cas.cz\/wp-content\/uploads\/2024\/07\/l7a51u878jdpoixdvn0j.png 1000w, https:\/\/fgu.cas.cz\/wp-content\/uploads\/2024\/07\/l7a51u878jdpoixdvn0j-300x107.png 300w, https:\/\/fgu.cas.cz\/wp-content\/uploads\/2024\/07\/l7a51u878jdpoixdvn0j-768x274.png 768w\" sizes=\"(max-width: 1000px) 100vw, 1000px\" title=\"\">\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-8d13471 elementor-widget elementor-widget-text-editor\" data-id=\"8d13471\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div class=\"main-image\"><em>Translational metabolism: Bridging the gap between research and medicine in metabolism<\/em><\/div><div class=\"content padding\">\u00a0<\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-211aab2 e-con-full e-flex e-con e-child\" data-id=\"211aab2\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-650442e elementor-widget elementor-widget-heading\" data-id=\"650442e\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">About the Laboratory<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b4f9d8b elementor-widget elementor-widget-text-editor\" data-id=\"b4f9d8b\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p style=\"text-align: left;\">Our research involves applying mass spectrometry-based techniques to perform metabolomics, lipidomic and proteomic analysis of various biological samples. We develop and use\u00a0<strong>liquid chromatography\u2013mass spectrometry-based (LC\u2013MS) methods<\/strong>\u00a0for in-depth characterization and quantification of complex lipids (<strong>lipidome<\/strong>), polar metabolites (<strong>metabolome<\/strong>), various exogenous compounds such as food components and drugs (<strong>exposome<\/strong>), and proteins (<strong>proteome<\/strong>). We also focus on improving data processing, automated data curation, statistical methods, and visualization of omics data.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b55d025 elementor-widget elementor-widget-text-editor\" data-id=\"b55d025\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>We have successfully integrated LC\u2013MS methods for the targeted and untargeted analysis of lipids, polar metabolites, and exposome compounds (LIMeX) for diverse sample types and used them for studies focused on cardiovascular diseases, type 2 diabetes, lipogenesis, circadian rhythms, and drug adherence.<\/p><p>We have also investigated the proteome of human teeth and saliva, their link to tooth decay, and proteins to tissue architecture at clubfoot and pulmonary hypertension. Posttranslational modifications of proteins are studied in connection to aging and disease of organisms.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-f613135 e-con-full e-flex e-con e-child\" data-id=\"f613135\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-a9aeb58 dual__bold elementor-widget elementor-widget-heading\" data-id=\"a9aeb58\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">PhD Program 2026\/2027 - Call for Applications<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-ffce7a5 elementor-widget elementor-widget-text-editor\" data-id=\"ffce7a5\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p style=\"text-align: left;\"><strong style=\"margin: 0px; padding: 0px; font-weight: bold; font-family: Arial;\"><br \/>Liquid chromatography-mass spectrometry for comprehensive characterization of the metabolome and lipidome of biological samples<br \/><\/strong><\/p><p>Over the last decade, mass spectrometry-based metabolomics and lipidomics have become the key platforms for the comprehensive profiling of polar metabolites and complex lipids in biological samples (plasma, serum, urine, and tissues). Coupling liquid chromatography to mass spectrometry (LC-MS) is the preferred technique in metabolomics and lipidomics, permitting effective compound separations and detection. However, there is still a lack of sufficient data on the metabolome and lipidome characterizing biofluids and tissues, which can be easily accessible and reused anytime for future studies. The Ph.D. project aims to focus on novel approaches for comprehensive characterization of the metabolome and lipidome in biological samples, specifically, (i) merging targeted and untargeted methods, (ii) increasing the coverage of spectral libraries used for metabolite annotation, and (iii) using bioinformatics tools for visualization and interpretation of the data obtained within metabolomics and lipidomics studies. The work will be conducted at the Institute of Physiology CAS and financially supported by grants (GACR, MSMT, AZV).<\/p><ul style=\"margin: 0px; padding: 0px; list-style-type: none; color: #404040; font-family: Arial, Arial, sans-serif; font-size: 14px; background-color: #ffffff;\"><li>Supervisor: T. \u010cajka (<a style=\"margin: 0px; padding: 0px; color: #61af94; outline: none;\" href=\"mailto:tomas.cajka@fgu.cas.cz\">tomas.cajka@fgu.cas.cz<\/a>)<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-90a8728 e-con-full e-flex e-con e-child\" data-id=\"90a8728\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-bfe5525 dual__bold elementor-widget elementor-widget-heading\" data-id=\"bfe5525\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">Main topics<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2c8c8c0 elementor-widget elementor-widget-text-editor\" data-id=\"2c8c8c0\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<ul style=\"margin: 0px; padding: 0px; list-style-type: none; color: #404040; font-family: Arial, Arial, sans-serif; font-size: 14px; background-color: #ffffff;\"><li style=\"margin: 0px; padding: 0px 0px 5px; list-style-position: inside; list-style-type: disc !important; text-align: left;\">Simple, fast, and robust protocols for metabolomics and proteomics projects<\/li><li style=\"margin: 0px; padding: 0px 0px 5px; list-style-position: inside; list-style-type: disc !important; text-align: left;\">Processing, curation, statistical analysis, and visualization of metabolomics data<\/li><li style=\"margin: 0px; padding: 0px 0px 5px; list-style-position: inside; list-style-type: disc !important; text-align: left;\">New separation methods (LC\u2013MS) for physiological research<\/li><li style=\"margin: 0px; padding: 0px 0px 5px; list-style-position: inside; list-style-type: disc !important; text-align: left;\">Metabolomics and proteomics for discovering new biomarkers of human health<\/li><li style=\"margin: 0px; padding: 0px 0px 5px; list-style-position: inside; list-style-type: disc !important; text-align: left;\">Analysis of extracellular matrix disorders: from proteins to tissue architecture at idiopathic pes equinovarus<\/li><li style=\"margin: 0px; padding: 0px 0px 5px; list-style-position: inside; list-style-type: disc !important; text-align: left;\">Mechanisms of pulmonary arterial wall remodeling during pulmonary hypertension development<\/li><li style=\"margin: 0px; padding: 0px 0px 5px; list-style-position: inside; list-style-type: disc !important; text-align: left;\">Posttranslational modifications of proteins during aging and disease (e.g., diabetes mellitus)<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b942421 dual__bold elementor-widget elementor-widget-heading\" data-id=\"b942421\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">Projects<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-46ce6f6 elementor-widget elementor-widget-text-editor\" data-id=\"46ce6f6\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p style=\"text-align: left;\">\n  <strong style=\"margin: 0px; padding: 0px; font-weight: bold; font-family: Arial;\">\n    Clinical metabolomics and lipidomics as innovative tools for the diagnosis and characterization of heart and kidney diseases (LUAUS24169)\n  <\/strong>\n<\/p>\n\n<ul style=\"margin: 0px; padding: 0px; list-style-type: none; color: #404040; font-family: Arial, Arial, sans-serif; font-size: 14px; background-color: #ffffff;\">\n  <li style=\"margin: 0px; padding: 0px 0px 5px; list-style-position: inside; list-style-type: disc !important; text-align: left;\">\n    Support: Ministry of Education, Youth and Sports\n  <\/li>\n  <li style=\"margin: 0px; padding: 0px 0px 5px; list-style-position: inside; list-style-type: disc !important; text-align: left;\">\n    PI: T. Cajka, Laboratory of Translational Metabolism\n  <\/li>\n  <li style=\"margin: 0px; padding: 0px 0px 5px; list-style-position: inside; list-style-type: disc !important; text-align: left;\">\n    Project goals: The goal of the project is to enhance cooperation and advance scientific activities between the Laboratory of Translational Metabolism and the Laboratory of Metabolomics at the Institute of Physiology of the Academy of Sciences of the Czech Republic, and the West Coast Metabolomics Center at the University of California, Davis. The focus of the collaboration lies in the domain of clinical metabolomics and lipidomics. The project aims to develop and optimize novel analytical methods, create spectral libraries, introduce data visualization tools, and apply this methodology for the diagnosis and characterization of heart and kidney diseases.\n  <\/li>\n<\/ul>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5187395 elementor-widget elementor-widget-text-editor\" data-id=\"5187395\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p style=\"text-align: left;\">\n  <strong style=\"margin: 0px; padding: 0px; font-weight: bold; font-family: Arial;\">\n    Correlates of protective immunity-driven investigation of malaria vaccine combination strategies (CAPTIVATE) (101081028)\n  <\/strong>\n<\/p>\n\n<ul style=\"margin: 0px; padding: 0px; list-style-type: none; color: #404040; font-family: Arial, Arial, sans-serif; font-size: 14px; background-color: #ffffff;\">\n  <li style=\"margin: 0px; padding: 0px 0px 5px; list-style-position: inside; list-style-type: disc !important; text-align: left;\">\n    Support: European Commission\n  <\/li>\n  <li style=\"margin: 0px; padding: 0px 0px 5px; list-style-position: inside; list-style-type: disc !important; text-align: left;\">\n    co-PI: T. Cajka, Laboratory of Translational Metabolism\n  <\/li>\n  <li style=\"margin: 0px; padding: 0px 0px 5px; list-style-position: inside; list-style-type: disc !important; text-align: left;\">\n    Project goals: In this project, combinations of 1) highly promising whole parasite vaccination approach targeting the liver (late-arresting GAP), 2) RTS,S (provided by GSK) and 3) mRNA versions of clinically evaluated and partially protective blood stage vaccine candidates (Rh5, AMA1-DiCo [sporozoite and blood stage]) will be evaluated in preclinical and small-scale human trials to discern the optimal combination for further clinical investigations.\n  <\/li>\n<\/ul>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2adcae0 elementor-widget elementor-widget-text-editor\" data-id=\"2adcae0\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p style=\"text-align: left;\">\n  <strong style=\"margin: 0px; padding: 0px; font-weight: bold; font-family: Arial;\">\n    Mechanisms of pulmonary vascular dysfunction in heart failure (LUNG-HF) (NU22-02-00161)\n  <\/strong>\n<\/p>\n\n<ul style=\"margin: 0px; padding: 0px; list-style-type: none; color: #404040; font-family: Arial, Arial, sans-serif; font-size: 14px; background-color: #ffffff;\">\n  <li style=\"margin: 0px; padding: 0px 0px 5px; list-style-position: inside; list-style-type: disc !important; text-align: left;\">\n    Support: Ministry of Health\n  <\/li>\n  <li style=\"margin: 0px; padding: 0px 0px 5px; list-style-position: inside; list-style-type: disc !important; text-align: left;\">\n    co-PI: T. Cajka, Laboratory of Translational Metabolism\n  <\/li>\n  <li style=\"margin: 0px; padding: 0px 0px 5px; list-style-position: inside; list-style-type: disc !important; text-align: left;\">\n    Project goals: Heart failure (HF) patients often develop pulmonary hypertension (PH) that leads to transition into a biventricular HF with poor prognosis. There are two PH components: 1) passive transmission of increased left atrial pressure, 2) HF-related pulmonary vascular dysfunction (PVD) with increased vascular resistance. Intriguingly, only some, but not all HF patients develop HF-related PVD. The mechanisms and non-invasive detection of HF-PVD are poorly understood and are the focus of the current grant application. Development of PVD is linked to insufficiently characterized metabolic factors that may be mediators of HF-PVD. Untargeted metabolomics is an emerging powerful platform for the discovery of pathways linked to diseases. Its specificity can be further enhanced using transpulmonary gradient sampling. Part A of the project aims to identify novel metabolites associated with the presence of PVD in patients with HF that can serve as biomarkers or targets and will provide biologic insights into PVD. Part C will assess the effects of reverting of metabolic alterations (identified in part A) by a drug\/diet on pulmonary vasculature in experimental HF-related PVD. The \u201cgold standard\u201d for the detection of PVD is right heart catheterization, which is invasive and risky. HF-related PVD is therefore often diagnosed late. There is a need for non-invasive tests that may help to detect PVD in early stages and can be done repeatedly. Recent advances in artificial intelligence (AI)-assisted automated quantitative analysis of lung texture from low-dose contrast-free high-resolution CT images allow to quantify lung water content, interstitial changes or vessel volume, and may provide clues for detection of HF-related PVD. Such an approach, not tested yet, will be utilized for the detection of HF-PVD (part B). Clinical and functional characteristics of lung circulation (exercise hemodynamics, diffusion capacity, perfusion) will be analyzed in relation to quantitative CT data.\n  <\/li>\n<\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-41a4035 elementor-widget elementor-widget-text-editor\" data-id=\"41a4035\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p style=\"text-align: left;\">\n  <strong style=\"margin: 0px; padding: 0px; font-weight: bold; font-family: Arial;\">\n    Identification of factors influencing adherence to pharmacotherapy in patients with type 2 diabetes using untargeted metabolomics (ENIGMA) (NU20-01-00186)\n  <\/strong>\n<\/p>\n\n<ul style=\"margin: 0px; padding: 0px; list-style-type: none; color: #404040; font-family: Arial, Arial, sans-serif; font-size: 14px; background-color: #ffffff;\">\n  <li style=\"margin: 0px; padding: 0px 0px 5px; list-style-position: inside; list-style-type: disc !important; text-align: left;\">\n    Support: Ministry of Health\n  <\/li>\n  <li style=\"margin: 0px; padding: 0px 0px 5px; list-style-position: inside; list-style-type: disc !important; text-align: left;\">\n    PI: T. Cajka, Laboratory of Translational Metabolism\n  <\/li>\n  <li style=\"margin: 0px; padding: 0px 0px 5px; list-style-position: inside; list-style-type: disc !important; text-align: left;\">\n    Project goals: Patient adherence along with pharmacokinetics are the most significant sources of variability in response to treatment. Thus, adherence monitoring should be an integral part of patient care, especially for chronic diseases such as type 2 diabetes (T2D). Another problem of adherence to drug treatment is whether the pharmacotherapy is used by the patient regularly. Furthermore, other substances (undeclared medications, food ingredients or drugs and alcohol), which often remain undetected in patient\u2019s history can fundamentally affect drug metabolism and patients\u2019 compliance. At present, there are no data available in the Czech Republic that would address this phenomenon in the T2D population. The hypothesis will be tested that the adherence to drug treatment in T2D patients may be effectively monitored by chemical analysis of selected drugs in blood plasma and that untargeted metabolomics may reveal biomarkers that would detect irregular use of pharmacotherapy. Thus, the project can significantly contribute to optimizing the treatment of T2D and other chronic diseases.\n  <\/li>\n<\/ul>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-29c7101 elementor-widget elementor-widget-text-editor\" data-id=\"29c7101\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p style=\"text-align: left;\">\n  <strong style=\"margin: 0px; padding: 0px; font-weight: bold; font-family: Arial;\">\n    Creation of 3D models of clubfoot and Dupuytren\u2019s disease and testing of anti-fibrotic substances (NU22-10-00072)\n  <\/strong>\n<\/p>\n\n<ul style=\"margin: 0px; padding: 0px; list-style-type: none; color: #404040; font-family: Arial, Arial, sans-serif; font-size: 14px; background-color: #ffffff;\">\n  <li style=\"margin: 0px; padding: 0px 0px 5px; list-style-position: inside; list-style-type: disc !important; text-align: left;\">\n    Support: Ministry of Health\n  <\/li>\n  <li style=\"margin: 0px; padding: 0px 0px 5px; list-style-position: inside; list-style-type: disc !important; text-align: left;\">\n    PI: A. Eckhardt, Laboratory of Translational Metabolism\n  <\/li>\n  <li style=\"margin: 0px; padding: 0px 0px 5px; list-style-position: inside; list-style-type: disc !important; text-align: left;\">\n    Project goals: This project builds on a previous project AZV (17-31564A). Idiopathic pes equinovarus (clubfoot) and Dupuytren&#8217;s&nbsp;disease (DD) are orthopedic deformities with unclear etiopathogenesis, characterized by contraction of the affected tissue. In a previous study, we demonstrated the presence of fibrotic tissue changes in the clubfoot tissue and we tested various antifibrotic substances that affect collagen production and deposition in a 2D cell culture. The main aim of the Project is to create 3D models of clubfoot and DD deformities based on the decellularized matrix from fibrotic tissues and reseeding the matrix with cells from the respective pathological tissues. The 3D models will be used to assess the effects of antifibrotic agents minoxidil and beta aminopropionitrile, which target the inhibition of collagen crosslinking and have the potential to loosen contracted fibrotic tissue. These agents will be applied dissolved in the medium and gradually released from biocompatible and biodegradable carriers. The effect of antifibrotic substances on cells cultured in these 3D models will be evaluated through analyses of the composition, morphology, and biomechanical parameters of the newly-deposited extracellular matrix, and also through differentiation, viability and other cell properties. The Project will also include a comparative proteomic, metabolomic and immunohistochemical analysis of native affected tissues of clubfoot and DD fibroproliferative diseases in order to identify specific and\/or common markers of ongoing pathological processes. These 3D models represent an important step for in vitro preclinical testing of potentially therapeutic agents for clubfoot and DD. Targeted antifibrotic treatment of the affected tissue could facilitate and streamline current non-invasive treatment of recurrences of severe clubfoot, and could lead to a new alternative for non-surgical treatment of DD.\n  <\/li>\n<\/ul>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-04bf3f2 elementor-widget elementor-widget-text-editor\" data-id=\"04bf3f2\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p style=\"text-align: left;\">\n  <strong style=\"margin: 0px; padding: 0px; font-weight: bold; font-family: Arial;\">\n    Hydrogen-deuterium exchange mass spectrometry (HDX-MS) to identify unknown metabolites detected by untargeted metabolomics (21-00477S)\n  <\/strong>\n<\/p>\n\n<ul style=\"margin: 0px; padding: 0px; list-style-type: none; color: #404040; font-family: Arial, Arial, sans-serif; font-size: 14px; background-color: #ffffff;\">\n  <li style=\"margin: 0px; padding: 0px 0px 5px; list-style-position: inside; list-style-type: disc !important; text-align: left;\">\n    Support: Czech Science Foundation\n  <\/li>\n  <li style=\"margin: 0px; padding: 0px 0px 5px; list-style-position: inside; list-style-type: disc !important; text-align: left;\">\n    PI: T. Cajka, Laboratory of Translational Metabolism\n  <\/li>\n  <li style=\"margin: 0px; padding: 0px 0px 5px; list-style-position: inside; list-style-type: disc !important; text-align: left;\">\n    Project goals: Untargeted metabolomics focuses on the analysis of all the detectable metabolites in a sample. Liquid chromatography-mass spectrometry (LC-MS)-based metabolomics can generate thousands of molecular features (retention time\u2013m\/z pairs) in biological samples per single analysis. However, only 10% of these features can be annotated and the rest of signals detected are unknowns. One of the most challenging aspects of metabolomics research is, therefore, the identification of unknown metabolites. The hypothesis will be tested that hydrogen-deuterium exchange mass spectrometry (HDX-MS) will dramatically improve the identification of unknown signals from untargeted metabolomics to derive new insights into biochemical and pathway interpretations of metabolomics data. To this end, we will optimize various LC-HDX-MS platforms for the profiling of polar metabolites and complex lipids and apply them to identify novel metabolites in mouse cecum, feces, and plasma after modification of gut microbiota with diet, antibiotics, and probiotics.\n  <\/li>\n<\/ul>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-be7f050 elementor-widget elementor-widget-text-editor\" data-id=\"be7f050\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p style=\"text-align: left;\">\n  <strong style=\"margin: 0px; padding: 0px; font-weight: bold; font-family: Arial;\">\n    Mapping of the rat circadian metabolome in brain and peripheral tissues during embryonic to postnatal development (20-21114S)\n  <\/strong>\n<\/p>\n\n<ul style=\"margin: 0px; padding: 0px; list-style-type: none; color: #404040; font-family: Arial, Arial, sans-serif; font-size: 14px; background-color: #ffffff;\">\n  <li style=\"margin: 0px; padding: 0px 0px 5px; list-style-position: inside; list-style-type: disc !important; text-align: left;\">\n    Support: Czech Science Foundation\n  <\/li>\n  <li style=\"margin: 0px; padding: 0px 0px 5px; list-style-position: inside; list-style-type: disc !important; text-align: left;\">\n    PI: T. Cajka, Laboratory of Translational Metabolism\n  <\/li>\n  <li style=\"margin: 0px; padding: 0px 0px 5px; list-style-position: inside; list-style-type: disc !important; text-align: left;\">\n    Project goals: The circadian rhythmicity during embryonic and postnatal development has been extensively studied for many years using transcriptomics. A progressive maturation of the circadian variation of the clock genes has been demonstrated. However, until now no study has focused on studying circadian rhythmicity during development at comprehensive metabolite-level insights. The hypothesis will be tested that the circadian metabolome is largely affected by developmental stage and global metabolomics and lipidomics profiling will provide a deep insight into dynamic metabolite relationships and capture metabolic alterations of rat tissues. We will perform 24-hr metabolomics and lipidomics profiling of three rat organs and plasma simultaneously at different developmental stages (embryonic E19, postnatal P2, P10, P20, P28). For P20 and P28 stages, this approach will be further extended for other types of rat tissues to generate a comprehensive atlas of circadian metabolism. Furthermore, a novel workflow to reduce false structures during identification of \u2018unknown\u2019 metabolites will be developed.\n  <\/li>\n<\/ul>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-770807f elementor-widget elementor-widget-text-editor\" data-id=\"770807f\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p style=\"text-align: left;\">\n  <strong style=\"margin: 0px; padding: 0px; font-weight: bold; font-family: Arial;\">\n    Metabolomics 2.0: Comprehensive analytical methods and bioinformatics tools for the study of circadian rhythms (LTAUSA19124)\n  <\/strong>\n<\/p>\n\n<ul style=\"margin: 0px; padding: 0px; list-style-type: none; color: #404040; font-family: Arial, Arial, sans-serif; font-size: 14px; background-color: #ffffff;\">\n  <li style=\"margin: 0px; padding: 0px 0px 5px; list-style-position: inside; list-style-type: disc !important; text-align: left;\">\n    Support: Ministry of Education, Youth and Sports\n  <\/li>\n  <li style=\"margin: 0px; padding: 0px 0px 5px; list-style-position: inside; list-style-type: disc !important; text-align: left;\">\n    PI: T. Cajka, Laboratory of Translational Metabolism\n  <\/li>\n  <li style=\"margin: 0px; padding: 0px 0px 5px; list-style-position: inside; list-style-type: disc !important; text-align: left;\">\n    Project goals: The aim of this project is to establish cooperation and active scientific activity between the Laboratory of Translational Metabolism, Laboratory of Metabolomics and Laboratory of Biological Rhythms (Institute of Physiology of the Czech Academy of Sciences) and the West Coast Metabolomics Center (University of California, Davis). The project focuses on the development of complex analytical methods and bioinformatics tools for the study of circadian rhythms. Recent improvements in chromatography and mass spectrometry methods, together with huge advances in computational approaches, means the time is right to develop second-generation metabolomics tools (Metabolomics 2.0) for the study of circadian rhythms. Scientific publications with detailed information needed for effective transfer of the methods will be available for other research institutions focusing on similar topics.\n  <\/li>\n<\/ul>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4f3dc0e elementor-widget elementor-widget-text-editor\" data-id=\"4f3dc0e\" data-element_type=\"widget\" body=\"\" font-family=\"\" font-size=\"\" color=\"\" line-height=\"\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p style=\"text-align: left;\">\n  <strong style=\"margin: 0px; padding: 0px; font-weight: bold; font-family: Arial;\">\n    National Institute for Research of Metabolic and Cardiovascular Diseases (LX22NPO5104)\n  <\/strong>\n<\/p>\n\n<ul style=\"margin: 0px; padding: 0px; list-style-type: none; color: #404040; font-family: Arial, Arial, sans-serif; font-size: 14px; background-color: #ffffff;\">\n  <li style=\"margin: 0px; padding: 0px 0px 5px; list-style-position: inside; list-style-type: disc !important; text-align: left;\">\n    Support: Ministry of Education, Youth and Sports\n  <\/li>\n  <li style=\"margin: 0px; padding: 0px 0px 5px; list-style-position: inside; list-style-type: disc !important; text-align: left;\">\n    Team member: T. Cajka, Laboratory of Translational Metabolism\n  <\/li>\n  <li style=\"margin: 0px; padding: 0px 0px 5px; list-style-position: inside; list-style-type: disc !important; text-align: left;\">\n    Project goals: The main purpose of the Exceles project is the establishment and start-up phase of CarDia, as a newly established national research platform integrating existing excellent personnel and advanced research infrastructure in the field of biomedical research on CVD, diabetes and obesity. The purpose is to develop research within the national institute to i) provide more targeted and safer therapeutic approaches ii) integrate this institute into the ERA and iii) profile its strategic role in eliminating the most socially and economically serious diseases in the Czech population, thereby contributing to building the resilience of the country.\n  <\/li>\n<\/ul>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-e720055 e-con-full e-flex e-con e-child\" data-id=\"e720055\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-b62862a elementor-widget elementor-widget-heading\" data-id=\"b62862a\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Projects<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-0d01bd7 elementor-grid-1 elementor-grid-tablet-1 elementor-grid-mobile-1 elementor-widget elementor-widget-loop-grid\" data-id=\"0d01bd7\" data-element_type=\"widget\" data-settings=\"{&quot;template_id&quot;:26040,&quot;columns&quot;:1,&quot;row_gap&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:10,&quot;sizes&quot;:[]},&quot;columns_tablet&quot;:1,&quot;row_gap_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:10,&quot;sizes&quot;:[]},&quot;_skin&quot;:&quot;post&quot;,&quot;columns_mobile&quot;:&quot;1&quot;,&quot;edit_handle_selector&quot;:&quot;[data-elementor-type=\\&quot;loop-item\\&quot;]&quot;,&quot;row_gap_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]}}\" data-widget_type=\"loop-grid.post\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-loop-container elementor-grid\" role=\"list\">\n\t\t<style id=\"loop-26040\">.elementor-26040 .elementor-element.elementor-element-004a4b0{--display:flex;--flex-direction:column;--container-widget-width:calc( ( 1 - var( --container-widget-flex-grow ) ) * 100% );--container-widget-height:initial;--container-widget-flex-grow:0;--container-widget-align-self:initial;--flex-wrap-mobile:wrap;--justify-content:space-between;--align-items:flex-start;--gap:15px 15px;--row-gap:15px;--column-gap:15px;border-style:solid;--border-style:solid;border-width:1px 1px 1px 1px;--border-top-width:1px;--border-right-width:1px;--border-bottom-width:1px;--border-left-width:1px;border-color:var( --e-global-color-d64be13 );--border-color:var( --e-global-color-d64be13 );--border-radius:10px 10px 10px 10px;box-shadow:0px 6px 10px 0px rgba(0, 0, 0, 0.1);--margin-top:0px;--margin-bottom:0px;--margin-left:0px;--margin-right:0px;--padding-top:20px;--padding-bottom:20px;--padding-left:20px;--padding-right:20px;}.elementor-26040 .elementor-element.elementor-element-004a4b0:not(.elementor-motion-effects-element-type-background), .elementor-26040 .elementor-element.elementor-element-004a4b0 > .elementor-motion-effects-container > .elementor-motion-effects-layer{background-color:var( --e-global-color-bbae344 );}.elementor-widget-heading .elementor-heading-title{font-family:var( --e-global-typography-primary-font-family ), Sans-serif;font-weight:var( --e-global-typography-primary-font-weight );line-height:var( --e-global-typography-primary-line-height );color:var( --e-global-color-primary );}.elementor-26040 .elementor-element.elementor-element-429f813 .elementor-heading-title{font-family:\"Barlow Condensed\", Sans-serif;font-size:24px;font-weight:600;text-transform:none;text-decoration:none;line-height:1.1em;}.elementor-widget-button .elementor-button{background-color:var( --e-global-color-accent );font-family:var( --e-global-typography-accent-font-family ), Sans-serif;font-size:var( --e-global-typography-accent-font-size );font-weight:var( --e-global-typography-accent-font-weight );text-decoration:var( --e-global-typography-accent-text-decoration );line-height:var( --e-global-typography-accent-line-height );}.elementor-26040 .elementor-element.elementor-element-1c3c2d8 .elementor-button{background-color:#00000000;fill:var( --e-global-color-primary );color:var( --e-global-color-primary );transition-duration:0.3s;border-style:solid;border-width:0px 0px 1px 0px;border-color:var( --e-global-color-text );border-radius:0px 0px 0px 0px;padding:0px 0px 5px 0px;}.elementor-26040 .elementor-element.elementor-element-1c3c2d8 .elementor-button:hover, .elementor-26040 .elementor-element.elementor-element-1c3c2d8 .elementor-button:focus{background-color:#00000000;color:var( --e-global-color-8d600d2 );border-color:var( --e-global-color-8d600d2 );}.elementor-26040 .elementor-element.elementor-element-1c3c2d8 .elementor-button-content-wrapper{flex-direction:row-reverse;}.elementor-26040 .elementor-element.elementor-element-1c3c2d8 .elementor-button .elementor-button-content-wrapper{gap:6px;}.elementor-26040 .elementor-element.elementor-element-1c3c2d8 .elementor-button:hover svg, .elementor-26040 .elementor-element.elementor-element-1c3c2d8 .elementor-button:focus svg{fill:var( --e-global-color-8d600d2 );}@media(min-width:768px){.elementor-26040 .elementor-element.elementor-element-004a4b0{--width:100%;}}@media(max-width:1024px){.elementor-26040 .elementor-element.elementor-element-004a4b0{--padding-top:20px;--padding-bottom:20px;--padding-left:20px;--padding-right:20px;}.elementor-widget-heading .elementor-heading-title{line-height:var( --e-global-typography-primary-line-height );}.elementor-26040 .elementor-element.elementor-element-429f813 .elementor-heading-title{font-size:24px;}.elementor-widget-button .elementor-button{font-size:var( --e-global-typography-accent-font-size );line-height:var( --e-global-typography-accent-line-height );}}@media(max-width:767px){.elementor-26040 .elementor-element.elementor-element-004a4b0{--padding-top:20px;--padding-bottom:20px;--padding-left:20px;--padding-right:20px;}.elementor-widget-heading .elementor-heading-title{line-height:var( --e-global-typography-primary-line-height );}.elementor-26040 .elementor-element.elementor-element-429f813 .elementor-heading-title{font-size:22px;}.elementor-widget-button .elementor-button{font-size:var( --e-global-typography-accent-font-size );line-height:var( --e-global-typography-accent-line-height );}}\/* Start custom CSS for heading, class: .elementor-element-429f813 *\/.elementor-26040 .elementor-element.elementor-element-429f813 a {\r\n    text-decoration: none;\r\n}\/* End custom CSS *\/\n\/* Start custom CSS for container, class: .elementor-element-004a4b0 *\/.elementor-26040 .elementor-element.elementor-element-004a4b0 {\n    height: 100%;\n}\/* End custom CSS *\/<\/style>\t\t<div data-elementor-type=\"loop-item\" data-elementor-id=\"26040\" class=\"elementor elementor-26040 elementor-1128 e-loop-item e-loop-item-30143 post-30143 vyzkumny-projekt type-vyzkumny-projekt status-publish hentry oddeleni-translational-metabolism stav-projektu-current-projects\" data-elementor-post-type=\"elementor_library\" data-custom-edit-handle=\"1\">\n\t\t\t<div class=\"elementor-element elementor-element-004a4b0 e-con-full e-flex e-con e-child\" data-id=\"004a4b0\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-429f813 elementor-widget elementor-widget-heading\" data-id=\"429f813\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h5 class=\"elementor-heading-title elementor-size-default\"><a href=\"https:\/\/fgu.cas.cz\/en\/research-project\/metabolomics-2-0\/\">Metabolomics 2.0<\/a><\/h5>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1c3c2d8 elementor-align-left button__text_arrow elementor-mobile-align-left elementor-widget elementor-widget-button\" data-id=\"1c3c2d8\" data-element_type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/fgu.cas.cz\/en\/research-project\/metabolomics-2-0\/\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t<span class=\"elementor-button-icon\">\n\t\t\t\t<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"16\" height=\"16\" viewBox=\"0 0 16 16\" fill=\"none\"><g id=\"arrow_forward_FILL0_wght400_GRAD0_opsz24 1\"><path id=\"Vector\" d=\"M10.7832 8.66663H2.6665V7.33329H10.7832L7.04984 3.59996L7.99984 2.66663L13.3332 7.99996L7.99984 13.3333L7.04984 12.4L10.7832 8.66663Z\" fill=\"black\"><\/path><\/g><\/svg>\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Read more<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-dc25d5b e-con-full e-flex e-con e-child\" data-id=\"dc25d5b\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-8595551 elementor-widget elementor-widget-heading\" data-id=\"8595551\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Achievements<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-e366542 custom_accordion  elementor-widget elementor-widget-accordion\" data-id=\"e366542\" data-element_type=\"widget\" data-widget_type=\"accordion.default\">\n\t\t\t\t\t\t\t<div class=\"elementor-accordion\">\n\t\t\t\t\t\t\t<div class=\"elementor-accordion-item\">\n\t\t\t\t\t<h5 id=\"elementor-tab-title-2381\" class=\"elementor-tab-title\" data-tab=\"1\" role=\"button\" aria-controls=\"elementor-tab-content-2381\" aria-expanded=\"false\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon elementor-accordion-icon-right\" aria-hidden=\"true\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon-closed\"><svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10.617\" height=\"16\" viewBox=\"0 0 10.617 16\"><g id=\"keyboard_backspace_24dp_FILL0_wght200_GRAD0_opsz24_1\" data-name=\"keyboard_backspace_24dp_FILL0_wght200_GRAD0_opsz24 1\" transform=\"translate(-6.691 -4)\"><path id=\"Vector\" d=\"M17.308,14.692,12,20,6.692,14.692l.708-.708,4.1,4.1V4h1V18.084l4.1-4.1Z\" fill=\"#1d1d1b\"><\/path><\/g><\/svg><\/span>\n\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon-opened\"><svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10.617\" height=\"16\" viewBox=\"0 0 10.617 16\"><g id=\"keyboard_backspace_24dp_FILL0_wght200_GRAD0_opsz24_1\" data-name=\"keyboard_backspace_24dp_FILL0_wght200_GRAD0_opsz24 1\" transform=\"translate(17.309 20) rotate(180)\"><path id=\"Vector\" d=\"M17.308,14.692,12,20,6.692,14.692l.708-.708,4.1,4.1V4h1V18.084l4.1-4.1Z\" fill=\"#1d1d1b\"><\/path><\/g><\/svg><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-accordion-title\" tabindex=\"0\">The Power List 2018 -- The Fab Forty<\/a>\n\t\t\t\t\t<\/h5>\n\t\t\t\t\t<div id=\"elementor-tab-content-2381\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"1\" role=\"region\" aria-labelledby=\"elementor-tab-title-2381\"><p>Assoc. Prof. Tomas Cajka has been ranked among 40 best scientists under 40 years in analytical chemistry. The ranking of the 40 most successful scientists was published in the October issue of <a href=\"https:\/\/theanalyticalscientist.com\/power-list\/2018\/\" target=\"_blank\" rel=\"noopener\">The Analytical Scientist<\/a>.<\/p><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-accordion-item\">\n\t\t\t\t\t<h5 id=\"elementor-tab-title-2382\" class=\"elementor-tab-title\" data-tab=\"2\" role=\"button\" aria-controls=\"elementor-tab-content-2382\" aria-expanded=\"false\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon elementor-accordion-icon-right\" aria-hidden=\"true\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon-closed\"><svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10.617\" height=\"16\" viewBox=\"0 0 10.617 16\"><g id=\"keyboard_backspace_24dp_FILL0_wght200_GRAD0_opsz24_1\" data-name=\"keyboard_backspace_24dp_FILL0_wght200_GRAD0_opsz24 1\" transform=\"translate(-6.691 -4)\"><path id=\"Vector\" d=\"M17.308,14.692,12,20,6.692,14.692l.708-.708,4.1,4.1V4h1V18.084l4.1-4.1Z\" fill=\"#1d1d1b\"><\/path><\/g><\/svg><\/span>\n\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon-opened\"><svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10.617\" height=\"16\" viewBox=\"0 0 10.617 16\"><g id=\"keyboard_backspace_24dp_FILL0_wght200_GRAD0_opsz24_1\" data-name=\"keyboard_backspace_24dp_FILL0_wght200_GRAD0_opsz24 1\" transform=\"translate(17.309 20) rotate(180)\"><path id=\"Vector\" d=\"M17.308,14.692,12,20,6.692,14.692l.708-.708,4.1,4.1V4h1V18.084l4.1-4.1Z\" fill=\"#1d1d1b\"><\/path><\/g><\/svg><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-accordion-title\" tabindex=\"0\">The Best Poster Award<\/a>\n\t\t\t\t\t<\/h5>\n\t\t\t\t\t<div id=\"elementor-tab-content-2382\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"2\" role=\"region\" aria-labelledby=\"elementor-tab-title-2382\"><p>Dr. Tom\u00e1\u0161 Novotn\u00fd was awarded \u201cThe Lester Lowe Award\u201d at the 40th World Orthopaedic Congerss, Muscat, Oman (2019, organizer: SICOT) for the poster \u201cHistological comparison of clubfoot deformity and Dupuytren&#8217;s&nbsp;disease fibroproliferation\u201d.<\/p><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-9750c69 e-con-full e-flex e-con e-child\" data-id=\"9750c69\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-f1379a3 elementor-widget elementor-widget-heading\" data-id=\"f1379a3\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Publications<\/h2>\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-754fc7f e-con-full e-flex e-con e-child\" data-id=\"754fc7f\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-837c252 elementor-widget__width-auto elementor-hidden-tablet elementor-hidden-mobile elementor-widget elementor-widget-facetwp-facet\" data-id=\"837c252\" data-element_type=\"widget\" data-widget_type=\"facetwp-facet.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\n        <div class=\"facet-wrap\">\n                            <h4>\n                    Publication year                <\/h4>\n                        <div class=\"facetwp-facet facetwp-facet-rok_vydani facetwp-type-fselect\" data-name=\"rok_vydani\" data-type=\"fselect\"><\/div>        <\/div>\n\n        \t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-970a40c elementor-widget__width-auto elementor-hidden-tablet elementor-hidden-mobile elementor-widget elementor-widget-facetwp-facet\" data-id=\"970a40c\" data-element_type=\"widget\" data-widget_type=\"facetwp-facet.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\n        <div class=\"facet-wrap\">\n                            <h4>\n                    Prestigious publication                <\/h4>\n                        <div class=\"facetwp-facet facetwp-facet-prestizni_publikace facetwp-type-fselect\" data-name=\"prestizni_publikace\" data-type=\"fselect\"><\/div>        <\/div>\n\n        \t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-8b063f3 elementor-widget__width-auto elementor-widget-tablet__width-inherit elementor-widget-mobile__width-initial elementor-widget elementor-widget-facetwp-facet\" data-id=\"8b063f3\" data-element_type=\"widget\" data-widget_type=\"facetwp-facet.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\n        <div class=\"facet-wrap\">\n                            <h4>\n                    Search publication                <\/h4>\n                        <div class=\"facetwp-facet facetwp-facet-vyhledavani facetwp-type-search\" data-name=\"vyhledavani\" 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--e-global-typography-accent-font-size );line-height:var( --e-global-typography-accent-line-height );}}<\/style>\t\t<div data-elementor-type=\"loop-item\" data-elementor-id=\"1140\" class=\"elementor elementor-1140 e-loop-item e-loop-item-53262 post-53262 publikace type-publikace status-publish hentry oddeleni-adipose-tissue-biology oddeleni-translational-metabolism typ-publikace-prestizni-publikace\" data-elementor-post-type=\"elementor_library\" data-custom-edit-handle=\"1\">\n\t\t\t<div class=\"elementor-element elementor-element-fdfbca6 e-con-full e-flex e-con e-parent\" data-id=\"fdfbca6\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-01e22d5 elementor-view-framed elementor-widget__width-initial elementor-shape-circle elementor-widget elementor-widget-icon\" data-id=\"01e22d5\" data-element_type=\"widget\" data-widget_type=\"icon.default\">\n\t\t\t\t\t\t\t<div class=\"elementor-icon-wrapper\">\n\t\t\t<div class=\"elementor-icon\">\n\t\t\t<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"14\" height=\"14\" viewBox=\"0 0 14 14\" fill=\"none\"><path d=\"M3.50016 12.8333C3.17933 12.8333 2.90468 12.7191 2.6762 12.4906C2.44773 12.2621 2.3335 11.9875 2.3335 11.6666V2.33329C2.3335 2.01246 2.44773 1.73781 2.6762 1.50933C2.90468 1.28086 3.17933 1.16663 3.50016 1.16663H10.5002C10.821 1.16663 11.0956 1.28086 11.3241 1.50933C11.5526 1.73781 11.6668 2.01246 11.6668 2.33329V11.6666C11.6668 11.9875 11.5526 12.2621 11.3241 12.4906C11.0956 12.7191 10.821 12.8333 10.5002 12.8333H3.50016ZM3.50016 11.6666H10.5002V2.33329H9.3335V6.41663L7.87516 5.54163L6.41683 6.41663V2.33329H3.50016V11.6666Z\" fill=\"white\"><\/path><\/svg>\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-7f15758 e-con-full e-flex e-con e-child\" data-id=\"7f15758\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-d82d22b elementor-widget__width-inherit elementor-widget elementor-widget-heading\" data-id=\"d82d22b\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<p class=\"elementor-heading-title elementor-size-default\">Janovsk\u00e1; Petra - Kobets; Tatyana - Steiner Mr\u00e1zov\u00e1; Lenka - Svobodov\u00e1; Michaela - Tesa\u0159ov\u00e1; M. - Kopeck\u00fd; P. - Zouhar; Petr - Rossmeisl; Martin - Str\u00e1neck\u00fd; V. - Kmoch; S. - Kopeck\u00fd; Jan\u00a0<i>Differential regulation of gene co-expression modules in muscles and liver of preterm newborns<\/i>. <strong>Frontiers in Cell and Developmental Biology.  2025; 13(30 Sep);  1645959<\/strong>. <\/p>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-f26a1ac elementor-widget elementor-widget-heading\" data-id=\"f26a1ac\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<p class=\"elementor-heading-title elementor-size-default\">IF = 4.3<\/p>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-ea5608b elementor-align-center button__text_arrow_large elementor-widget elementor-widget-button\" data-id=\"ea5608b\" data-element_type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/hdl.handle.net\/11104\/0371301\" target=\"_blank\" rel=\"noopener\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t<span class=\"elementor-button-icon\">\n\t\t\t\t<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"16\" height=\"16\" viewBox=\"0 0 16 16\" fill=\"none\"><g id=\"arrow_forward_FILL0_wght400_GRAD0_opsz24 1\"><path id=\"Vector\" d=\"M10.7832 8.66663H2.6665V7.33329H10.7832L7.04984 3.59996L7.99984 2.66663L13.3332 7.99996L7.99984 13.3333L7.04984 12.4L10.7832 8.66663Z\" fill=\"black\"><\/path><\/g><\/svg>\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">ASEP<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-bdfa0a7 elementor-align-center button__text_arrow_large elementor-widget elementor-widget-button\" data-id=\"bdfa0a7\" data-element_type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/dx.doi.org\/10.3389\/fcell.2025.1645959\" target=\"_blank\" rel=\"noopener\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t<span class=\"elementor-button-icon\">\n\t\t\t\t<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"16\" height=\"16\" viewBox=\"0 0 16 16\" fill=\"none\"><g id=\"arrow_forward_FILL0_wght400_GRAD0_opsz24 1\"><path id=\"Vector\" d=\"M10.7832 8.66663H2.6665V7.33329H10.7832L7.04984 3.59996L7.99984 2.66663L13.3332 7.99996L7.99984 13.3333L7.04984 12.4L10.7832 8.66663Z\" fill=\"black\"><\/path><\/g><\/svg>\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">DOI<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div data-elementor-type=\"loop-item\" data-elementor-id=\"1140\" class=\"elementor elementor-1140 e-loop-item e-loop-item-53267 post-53267 publikace type-publikace status-publish hentry oddeleni-adipose-tissue-biology oddeleni-molecular-physiology-of-bone oddeleni-translational-metabolism typ-publikace-prestizni-publikace\" data-elementor-post-type=\"elementor_library\" data-custom-edit-handle=\"1\">\n\t\t\t<div class=\"elementor-element elementor-element-fdfbca6 e-con-full e-flex e-con e-parent\" data-id=\"fdfbca6\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-01e22d5 elementor-view-framed elementor-widget__width-initial elementor-shape-circle elementor-widget elementor-widget-icon\" data-id=\"01e22d5\" data-element_type=\"widget\" data-widget_type=\"icon.default\">\n\t\t\t\t\t\t\t<div class=\"elementor-icon-wrapper\">\n\t\t\t<div class=\"elementor-icon\">\n\t\t\t<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"14\" height=\"14\" viewBox=\"0 0 14 14\" fill=\"none\"><path d=\"M3.50016 12.8333C3.17933 12.8333 2.90468 12.7191 2.6762 12.4906C2.44773 12.2621 2.3335 11.9875 2.3335 11.6666V2.33329C2.3335 2.01246 2.44773 1.73781 2.6762 1.50933C2.90468 1.28086 3.17933 1.16663 3.50016 1.16663H10.5002C10.821 1.16663 11.0956 1.28086 11.3241 1.50933C11.5526 1.73781 11.6668 2.01246 11.6668 2.33329V11.6666C11.6668 11.9875 11.5526 12.2621 11.3241 12.4906C11.0956 12.7191 10.821 12.8333 10.5002 12.8333H3.50016ZM3.50016 11.6666H10.5002V2.33329H9.3335V6.41663L7.87516 5.54163L6.41683 6.41663V2.33329H3.50016V11.6666Z\" fill=\"white\"><\/path><\/svg>\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-7f15758 e-con-full e-flex e-con e-child\" data-id=\"7f15758\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-d82d22b elementor-widget__width-inherit elementor-widget elementor-widget-heading\" data-id=\"d82d22b\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<p class=\"elementor-heading-title elementor-size-default\">D\u017eubanov\u00e1; Martina - Feren\u010d\u00e1kov\u00e1; Michaela - Nguyen; Dung Kim - Bardov\u00e1; Kristina - Golovina; Elena - Fehervary; H. - Be\u0148ov\u00e1; Andrea - Odaba\u015fi; Yusuf - Naraine; Ravindra - \u0160indelka; Radek - \u0160poutil; Franti\u0161ek - Proch\u00e1zka; Jan - \u010cajka; Tom\u00e1\u0161 - van Lenthe; G. H. - Sarkis; R. - Naveiras; O. - Rossmeisl; Martin - Kopeck\u00fd; Jan - Tencerov\u00e1; Michaela\u00a0<i>Glutamine: A novel player in maintaining skeletal strength and body fitness in obese mice<\/i>. <strong>Clinical Nutrition.  2025; 54(Nov); 162-176<\/strong>. <\/p>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-f26a1ac elementor-widget elementor-widget-heading\" data-id=\"f26a1ac\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<p class=\"elementor-heading-title elementor-size-default\">IF = 7.4<\/p>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-ea5608b elementor-align-center button__text_arrow_large elementor-widget elementor-widget-button\" data-id=\"ea5608b\" data-element_type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/hdl.handle.net\/11104\/0370940\" target=\"_blank\" rel=\"noopener\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t<span class=\"elementor-button-icon\">\n\t\t\t\t<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"16\" height=\"16\" viewBox=\"0 0 16 16\" fill=\"none\"><g id=\"arrow_forward_FILL0_wght400_GRAD0_opsz24 1\"><path id=\"Vector\" d=\"M10.7832 8.66663H2.6665V7.33329H10.7832L7.04984 3.59996L7.99984 2.66663L13.3332 7.99996L7.99984 13.3333L7.04984 12.4L10.7832 8.66663Z\" fill=\"black\"><\/path><\/g><\/svg>\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">ASEP<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-bdfa0a7 elementor-align-center button__text_arrow_large elementor-widget elementor-widget-button\" data-id=\"bdfa0a7\" data-element_type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/dx.doi.org\/10.1016\/j.clnu.2025.09.018\" target=\"_blank\" rel=\"noopener\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t<span class=\"elementor-button-icon\">\n\t\t\t\t<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"16\" height=\"16\" viewBox=\"0 0 16 16\" fill=\"none\"><g id=\"arrow_forward_FILL0_wght400_GRAD0_opsz24 1\"><path id=\"Vector\" d=\"M10.7832 8.66663H2.6665V7.33329H10.7832L7.04984 3.59996L7.99984 2.66663L13.3332 7.99996L7.99984 13.3333L7.04984 12.4L10.7832 8.66663Z\" fill=\"black\"><\/path><\/g><\/svg>\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">DOI<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div data-elementor-type=\"loop-item\" data-elementor-id=\"1140\" class=\"elementor elementor-1140 e-loop-item e-loop-item-49265 post-49265 publikace type-publikace status-publish hentry oddeleni-biological-rhythms oddeleni-metabolism-of-bioactive-lipids oddeleni-translational-metabolism typ-publikace-prestizni-publikace\" data-elementor-post-type=\"elementor_library\" data-custom-edit-handle=\"1\">\n\t\t\t<div class=\"elementor-element elementor-element-fdfbca6 e-con-full e-flex e-con e-parent\" data-id=\"fdfbca6\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-01e22d5 elementor-view-framed elementor-widget__width-initial elementor-shape-circle elementor-widget elementor-widget-icon\" data-id=\"01e22d5\" data-element_type=\"widget\" data-widget_type=\"icon.default\">\n\t\t\t\t\t\t\t<div class=\"elementor-icon-wrapper\">\n\t\t\t<div class=\"elementor-icon\">\n\t\t\t<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"14\" height=\"14\" viewBox=\"0 0 14 14\" fill=\"none\"><path d=\"M3.50016 12.8333C3.17933 12.8333 2.90468 12.7191 2.6762 12.4906C2.44773 12.2621 2.3335 11.9875 2.3335 11.6666V2.33329C2.3335 2.01246 2.44773 1.73781 2.6762 1.50933C2.90468 1.28086 3.17933 1.16663 3.50016 1.16663H10.5002C10.821 1.16663 11.0956 1.28086 11.3241 1.50933C11.5526 1.73781 11.6668 2.01246 11.6668 2.33329V11.6666C11.6668 11.9875 11.5526 12.2621 11.3241 12.4906C11.0956 12.7191 10.821 12.8333 10.5002 12.8333H3.50016ZM3.50016 11.6666H10.5002V2.33329H9.3335V6.41663L7.87516 5.54163L6.41683 6.41663V2.33329H3.50016V11.6666Z\" fill=\"white\"><\/path><\/svg>\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-7f15758 e-con-full e-flex e-con e-child\" data-id=\"7f15758\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-d82d22b elementor-widget__width-inherit elementor-widget elementor-widget-heading\" data-id=\"d82d22b\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<p class=\"elementor-heading-title elementor-size-default\">Rudl Kulhav\u00e1; Lucie - Houdek; Pavel - Nov\u00e1kov\u00e1; Michaela - Hricko; Ji\u0159\u00ed - Pau\u010dov\u00e1; Michaela - Kuda; Ond\u0159ej - Sl\u00e1dek; Martin - Fiehn; O. - Sumov\u00e1; Alena - \u010cajka; Tom\u00e1\u0161\u00a0<i>Circadian ontogenetic metabolomics atlas: an interactive resource with insights from rat plasma; tissues; and feces<\/i>. <strong>Cellular and Molecular Life Sciences.  2025; 82(28 Jun);  264<\/strong>. <\/p>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-f26a1ac elementor-widget elementor-widget-heading\" data-id=\"f26a1ac\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<p class=\"elementor-heading-title elementor-size-default\">IF = 6.2<\/p>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-ea5608b elementor-align-center button__text_arrow_large elementor-widget elementor-widget-button\" data-id=\"ea5608b\" data-element_type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/hdl.handle.net\/11104\/0367980\" target=\"_blank\" rel=\"noopener\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t<span class=\"elementor-button-icon\">\n\t\t\t\t<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"16\" height=\"16\" viewBox=\"0 0 16 16\" fill=\"none\"><g id=\"arrow_forward_FILL0_wght400_GRAD0_opsz24 1\"><path id=\"Vector\" d=\"M10.7832 8.66663H2.6665V7.33329H10.7832L7.04984 3.59996L7.99984 2.66663L13.3332 7.99996L7.99984 13.3333L7.04984 12.4L10.7832 8.66663Z\" fill=\"black\"><\/path><\/g><\/svg>\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">ASEP<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-bdfa0a7 elementor-align-center button__text_arrow_large elementor-widget elementor-widget-button\" data-id=\"bdfa0a7\" data-element_type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/dx.doi.org\/10.1007\/s00018-025-05783-w\" target=\"_blank\" rel=\"noopener\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t<span class=\"elementor-button-icon\">\n\t\t\t\t<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"16\" height=\"16\" viewBox=\"0 0 16 16\" fill=\"none\"><g id=\"arrow_forward_FILL0_wght400_GRAD0_opsz24 1\"><path id=\"Vector\" d=\"M10.7832 8.66663H2.6665V7.33329H10.7832L7.04984 3.59996L7.99984 2.66663L13.3332 7.99996L7.99984 13.3333L7.04984 12.4L10.7832 8.66663Z\" fill=\"black\"><\/path><\/g><\/svg>\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">DOI<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div data-elementor-type=\"loop-item\" data-elementor-id=\"1140\" class=\"elementor elementor-1140 e-loop-item e-loop-item-49266 post-49266 publikace type-publikace status-publish hentry oddeleni-biological-rhythms oddeleni-translational-metabolism typ-publikace-prestizni-publikace\" data-elementor-post-type=\"elementor_library\" data-custom-edit-handle=\"1\">\n\t\t\t<div class=\"elementor-element elementor-element-fdfbca6 e-con-full e-flex e-con e-parent\" data-id=\"fdfbca6\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-01e22d5 elementor-view-framed elementor-widget__width-initial elementor-shape-circle elementor-widget elementor-widget-icon\" data-id=\"01e22d5\" data-element_type=\"widget\" data-widget_type=\"icon.default\">\n\t\t\t\t\t\t\t<div class=\"elementor-icon-wrapper\">\n\t\t\t<div class=\"elementor-icon\">\n\t\t\t<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"14\" height=\"14\" viewBox=\"0 0 14 14\" fill=\"none\"><path d=\"M3.50016 12.8333C3.17933 12.8333 2.90468 12.7191 2.6762 12.4906C2.44773 12.2621 2.3335 11.9875 2.3335 11.6666V2.33329C2.3335 2.01246 2.44773 1.73781 2.6762 1.50933C2.90468 1.28086 3.17933 1.16663 3.50016 1.16663H10.5002C10.821 1.16663 11.0956 1.28086 11.3241 1.50933C11.5526 1.73781 11.6668 2.01246 11.6668 2.33329V11.6666C11.6668 11.9875 11.5526 12.2621 11.3241 12.4906C11.0956 12.7191 10.821 12.8333 10.5002 12.8333H3.50016ZM3.50016 11.6666H10.5002V2.33329H9.3335V6.41663L7.87516 5.54163L6.41683 6.41663V2.33329H3.50016V11.6666Z\" fill=\"white\"><\/path><\/svg>\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-7f15758 e-con-full e-flex e-con e-child\" data-id=\"7f15758\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-d82d22b elementor-widget__width-inherit elementor-widget elementor-widget-heading\" data-id=\"d82d22b\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<p class=\"elementor-heading-title elementor-size-default\">Sl\u00e1dek; Martin - Houdek; Pavel - \u010cajka; Tom\u00e1\u0161 - Sumov\u00e1; Alena\u00a0<i>Maternal food-derived signals oscillate in the fetal suprachiasmatic nucleus before its circadian clock develops<\/i>. <strong>PLOS Biology.  2025; 23(9);  e3003404<\/strong>. <\/p>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-f26a1ac elementor-widget elementor-widget-heading\" data-id=\"f26a1ac\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<p class=\"elementor-heading-title elementor-size-default\">IF = 7.2<\/p>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-ea5608b elementor-align-center button__text_arrow_large elementor-widget elementor-widget-button\" data-id=\"ea5608b\" data-element_type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/hdl.handle.net\/11104\/0369830\" target=\"_blank\" rel=\"noopener\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t<span class=\"elementor-button-icon\">\n\t\t\t\t<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"16\" height=\"16\" viewBox=\"0 0 16 16\" fill=\"none\"><g id=\"arrow_forward_FILL0_wght400_GRAD0_opsz24 1\"><path id=\"Vector\" d=\"M10.7832 8.66663H2.6665V7.33329H10.7832L7.04984 3.59996L7.99984 2.66663L13.3332 7.99996L7.99984 13.3333L7.04984 12.4L10.7832 8.66663Z\" fill=\"black\"><\/path><\/g><\/svg>\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">ASEP<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-bdfa0a7 elementor-align-center button__text_arrow_large elementor-widget elementor-widget-button\" data-id=\"bdfa0a7\" data-element_type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/dx.doi.org\/10.1371\/journal.pbio.3003404\" target=\"_blank\" rel=\"noopener\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t<span class=\"elementor-button-icon\">\n\t\t\t\t<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"16\" height=\"16\" viewBox=\"0 0 16 16\" fill=\"none\"><g id=\"arrow_forward_FILL0_wght400_GRAD0_opsz24 1\"><path id=\"Vector\" d=\"M10.7832 8.66663H2.6665V7.33329H10.7832L7.04984 3.59996L7.99984 2.66663L13.3332 7.99996L7.99984 13.3333L7.04984 12.4L10.7832 8.66663Z\" fill=\"black\"><\/path><\/g><\/svg>\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">DOI<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div data-elementor-type=\"loop-item\" data-elementor-id=\"1140\" class=\"elementor elementor-1140 e-loop-item e-loop-item-46172 post-46172 publikace type-publikace status-publish hentry oddeleni-adipose-tissue-biology oddeleni-translational-metabolism typ-publikace-prestizni-publikace\" data-elementor-post-type=\"elementor_library\" data-custom-edit-handle=\"1\">\n\t\t\t<div class=\"elementor-element elementor-element-fdfbca6 e-con-full e-flex e-con e-parent\" data-id=\"fdfbca6\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-01e22d5 elementor-view-framed elementor-widget__width-initial elementor-shape-circle elementor-widget elementor-widget-icon\" data-id=\"01e22d5\" data-element_type=\"widget\" data-widget_type=\"icon.default\">\n\t\t\t\t\t\t\t<div class=\"elementor-icon-wrapper\">\n\t\t\t<div class=\"elementor-icon\">\n\t\t\t<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"14\" height=\"14\" viewBox=\"0 0 14 14\" fill=\"none\"><path d=\"M3.50016 12.8333C3.17933 12.8333 2.90468 12.7191 2.6762 12.4906C2.44773 12.2621 2.3335 11.9875 2.3335 11.6666V2.33329C2.3335 2.01246 2.44773 1.73781 2.6762 1.50933C2.90468 1.28086 3.17933 1.16663 3.50016 1.16663H10.5002C10.821 1.16663 11.0956 1.28086 11.3241 1.50933C11.5526 1.73781 11.6668 2.01246 11.6668 2.33329V11.6666C11.6668 11.9875 11.5526 12.2621 11.3241 12.4906C11.0956 12.7191 10.821 12.8333 10.5002 12.8333H3.50016ZM3.50016 11.6666H10.5002V2.33329H9.3335V6.41663L7.87516 5.54163L6.41683 6.41663V2.33329H3.50016V11.6666Z\" fill=\"white\"><\/path><\/svg>\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-7f15758 e-con-full e-flex e-con e-child\" data-id=\"7f15758\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-d82d22b elementor-widget__width-inherit elementor-widget elementor-widget-heading\" data-id=\"d82d22b\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<p class=\"elementor-heading-title elementor-size-default\">Pomar; C. A. - Zouhar; Petr - DeLucas; M. - \u010cajka; Tom\u00e1\u0161 - Cobo; P. - Jim\u00e9nez-Cabanillas; M. V. - Bibiloni; P. - Kopeck\u00fd; Jan - Palou; A. - Serra; F. - S\u00e1nchez; J. - Pic\u00f3; C.\u00a0<i>Breast Milk Metabolomic Profile Is Associated With Maternal Overweight\/Obesity Status or Adherence to Mediterranean Diet and Infant Weight Gain During the First Month of Lactation<\/i>. <strong>Food Frontiers.  2025; 6(3); 1454-1468<\/strong>. <\/p>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-f26a1ac elementor-widget elementor-widget-heading\" data-id=\"f26a1ac\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<p class=\"elementor-heading-title elementor-size-default\">IF = 6.9<\/p>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-ea5608b elementor-align-center button__text_arrow_large elementor-widget elementor-widget-button\" data-id=\"ea5608b\" data-element_type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/hdl.handle.net\/11104\/0367550\" target=\"_blank\" rel=\"noopener\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t<span class=\"elementor-button-icon\">\n\t\t\t\t<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"16\" height=\"16\" viewBox=\"0 0 16 16\" fill=\"none\"><g id=\"arrow_forward_FILL0_wght400_GRAD0_opsz24 1\"><path id=\"Vector\" d=\"M10.7832 8.66663H2.6665V7.33329H10.7832L7.04984 3.59996L7.99984 2.66663L13.3332 7.99996L7.99984 13.3333L7.04984 12.4L10.7832 8.66663Z\" fill=\"black\"><\/path><\/g><\/svg>\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">ASEP<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-bdfa0a7 elementor-align-center button__text_arrow_large elementor-widget elementor-widget-button\" data-id=\"bdfa0a7\" data-element_type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/dx.doi.org\/10.1002\/fft2.70017\" target=\"_blank\" rel=\"noopener\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t<span class=\"elementor-button-icon\">\n\t\t\t\t<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"16\" height=\"16\" viewBox=\"0 0 16 16\" fill=\"none\"><g id=\"arrow_forward_FILL0_wght400_GRAD0_opsz24 1\"><path id=\"Vector\" d=\"M10.7832 8.66663H2.6665V7.33329H10.7832L7.04984 3.59996L7.99984 2.66663L13.3332 7.99996L7.99984 13.3333L7.04984 12.4L10.7832 8.66663Z\" fill=\"black\"><\/path><\/g><\/svg>\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">DOI<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div data-elementor-type=\"loop-item\" data-elementor-id=\"1140\" class=\"elementor elementor-1140 e-loop-item e-loop-item-46174 post-46174 publikace type-publikace status-publish hentry oddeleni-adipose-tissue-biology oddeleni-translational-metabolism typ-publikace-standardni-publikace\" data-elementor-post-type=\"elementor_library\" data-custom-edit-handle=\"1\">\n\t\t\t<div class=\"elementor-element elementor-element-fdfbca6 e-con-full e-flex e-con e-parent\" data-id=\"fdfbca6\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-01e22d5 elementor-view-framed elementor-widget__width-initial elementor-shape-circle elementor-widget elementor-widget-icon\" data-id=\"01e22d5\" data-element_type=\"widget\" data-widget_type=\"icon.default\">\n\t\t\t\t\t\t\t<div class=\"elementor-icon-wrapper\">\n\t\t\t<div class=\"elementor-icon\">\n\t\t\t<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"14\" height=\"14\" viewBox=\"0 0 14 14\" fill=\"none\"><path d=\"M3.50016 12.8333C3.17933 12.8333 2.90468 12.7191 2.6762 12.4906C2.44773 12.2621 2.3335 11.9875 2.3335 11.6666V2.33329C2.3335 2.01246 2.44773 1.73781 2.6762 1.50933C2.90468 1.28086 3.17933 1.16663 3.50016 1.16663H10.5002C10.821 1.16663 11.0956 1.28086 11.3241 1.50933C11.5526 1.73781 11.6668 2.01246 11.6668 2.33329V11.6666C11.6668 11.9875 11.5526 12.2621 11.3241 12.4906C11.0956 12.7191 10.821 12.8333 10.5002 12.8333H3.50016ZM3.50016 11.6666H10.5002V2.33329H9.3335V6.41663L7.87516 5.54163L6.41683 6.41663V2.33329H3.50016V11.6666Z\" fill=\"white\"><\/path><\/svg>\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-7f15758 e-con-full e-flex e-con e-child\" data-id=\"7f15758\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-d82d22b elementor-widget__width-inherit elementor-widget elementor-widget-heading\" data-id=\"d82d22b\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<p class=\"elementor-heading-title elementor-size-default\">Janovsk\u00e1; Petra - Bardov\u00e1; Kristina - Prouzov\u00e1; Z. - Irodenko; Ilaria - Kobets; Tatyana - Haasov\u00e1; Eli\u0161ka - Steiner Mr\u00e1zov\u00e1; Lenka - Str\u00e1neck\u00fd; V. - Kmoch; S. - Rossmeisl; Martin - Zouhar; Petr - Kopeck\u00fd; Jan\u00a0<i>Faster postnatal decline in hepatic erythropoiesis than granulopoiesis in human newborns<\/i>. <strong>Frontiers in Pediatrics.  2025; 13(20 May);  1572836<\/strong>. <\/p>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-f26a1ac elementor-widget elementor-widget-heading\" data-id=\"f26a1ac\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<p class=\"elementor-heading-title elementor-size-default\">IF = 2.0<\/p>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-ea5608b elementor-align-center button__text_arrow_large elementor-widget elementor-widget-button\" data-id=\"ea5608b\" data-element_type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/hdl.handle.net\/11104\/0367552\" target=\"_blank\" rel=\"noopener\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t<span class=\"elementor-button-icon\">\n\t\t\t\t<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"16\" height=\"16\" viewBox=\"0 0 16 16\" fill=\"none\"><g id=\"arrow_forward_FILL0_wght400_GRAD0_opsz24 1\"><path id=\"Vector\" d=\"M10.7832 8.66663H2.6665V7.33329H10.7832L7.04984 3.59996L7.99984 2.66663L13.3332 7.99996L7.99984 13.3333L7.04984 12.4L10.7832 8.66663Z\" fill=\"black\"><\/path><\/g><\/svg>\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">ASEP<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-bdfa0a7 elementor-align-center button__text_arrow_large elementor-widget elementor-widget-button\" data-id=\"bdfa0a7\" data-element_type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/dx.doi.org\/10.3389\/fped.2025.1572836\" target=\"_blank\" rel=\"noopener\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t<span class=\"elementor-button-icon\">\n\t\t\t\t<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"16\" height=\"16\" viewBox=\"0 0 16 16\" fill=\"none\"><g id=\"arrow_forward_FILL0_wght400_GRAD0_opsz24 1\"><path id=\"Vector\" d=\"M10.7832 8.66663H2.6665V7.33329H10.7832L7.04984 3.59996L7.99984 2.66663L13.3332 7.99996L7.99984 13.3333L7.04984 12.4L10.7832 8.66663Z\" fill=\"black\"><\/path><\/g><\/svg>\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">DOI<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1551d91 elementor-widget elementor-widget-facetwp-facet\" data-id=\"1551d91\" data-element_type=\"widget\" data-widget_type=\"facetwp-facet.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\n        <div class=\"facet-wrap\">\n                        <div class=\"facetwp-facet facetwp-facet-strankovani facetwp-type-pager\" data-name=\"strankovani\" data-type=\"pager\"><\/div>        <\/div>\n\n        \t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-62bc508 e-con-full e-flex e-con e-child\" data-id=\"62bc508\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-b77a05b elementor-widget elementor-widget-heading\" data-id=\"b77a05b\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">People<\/h2>\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-9d962a9 e-con-full e-flex e-con e-child\" data-id=\"9d962a9\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-ddf949e dual__bold elementor-widget elementor-widget-heading\" data-id=\"ddf949e\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">Head of Laboratory<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-d7d7132 elementor-grid-2 elementor-grid-tablet-2 elementor-grid-mobile-1 elementor-widget elementor-widget-loop-grid\" data-id=\"d7d7132\" data-element_type=\"widget\" data-settings=\"{&quot;template_id&quot;:1210,&quot;columns&quot;:2,&quot;row_gap&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:20,&quot;sizes&quot;:[]},&quot;columns_tablet&quot;:2,&quot;row_gap_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:10,&quot;sizes&quot;:[]},&quot;_skin&quot;:&quot;post&quot;,&quot;columns_mobile&quot;:&quot;1&quot;,&quot;edit_handle_selector&quot;:&quot;[data-elementor-type=\\&quot;loop-item\\&quot;]&quot;,&quot;row_gap_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]}}\" data-widget_type=\"loop-grid.post\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-loop-container elementor-grid\" role=\"list\">\n\t\t<style id=\"loop-1210\">.elementor-1210 .elementor-element.elementor-element-237f3e9{--display:flex;--flex-direction:row;--container-widget-width:calc( ( 1 - var( --container-widget-flex-grow ) ) * 100% );--container-widget-height:100%;--container-widget-flex-grow:1;--container-widget-align-self:stretch;--flex-wrap-mobile:wrap;--justify-content:flex-start;--align-items:center;--gap:10px 10px;--row-gap:10px;--column-gap:10px;border-style:solid;--border-style:solid;border-width:1px 1px 1px 1px;--border-top-width:1px;--border-right-width:1px;--border-bottom-width:1px;--border-left-width:1px;border-color:var( --e-global-color-d64be13 );--border-color:var( --e-global-color-d64be13 );--border-radius:10px 10px 10px 10px;box-shadow:0px 6px 10px 0px rgba(0, 0, 0, 0.1);--margin-top:0px;--margin-bottom:0px;--margin-left:0px;--margin-right:0px;--padding-top:0px;--padding-bottom:0px;--padding-left:0px;--padding-right:0px;}.elementor-1210 .elementor-element.elementor-element-237f3e9:not(.elementor-motion-effects-element-type-background), .elementor-1210 .elementor-element.elementor-element-237f3e9 > .elementor-motion-effects-container > .elementor-motion-effects-layer{background-color:var( --e-global-color-bbae344 );}.elementor-widget-image .widget-image-caption{color:var( --e-global-color-text );font-family:var( --e-global-typography-text-font-family ), Sans-serif;font-size:var( --e-global-typography-text-font-size );font-weight:var( --e-global-typography-text-font-weight );line-height:var( --e-global-typography-text-line-height );}.elementor-1210 .elementor-element.elementor-element-9ce683f{width:var( --container-widget-width, 90px );max-width:90px;padding:5px 5px 5px 5px;--container-widget-width:90px;--container-widget-flex-grow:0;}.elementor-1210 .elementor-element.elementor-element-9ce683f.elementor-element{--flex-grow:0;--flex-shrink:0;}.elementor-1210 .elementor-element.elementor-element-9ce683f img{width:100%;max-width:80px;height:80px;object-fit:cover;object-position:top center;border-radius:100px 100px 100px 100px;}.elementor-1210 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);}.elementor-1210 .elementor-element.elementor-element-0040c42{--padding-top:2px;--padding-bottom:2px;--padding-left:5px;--padding-right:0px;}.elementor-widget-heading .elementor-heading-title{line-height:var( --e-global-typography-primary-line-height );}.elementor-1210 .elementor-element.elementor-element-ad7a981 .elementor-heading-title{font-size:var( --e-global-typography-74d688f-font-size );line-height:var( --e-global-typography-74d688f-line-height );}.elementor-1210 .elementor-element.elementor-element-551f794 .elementor-heading-title{font-size:var( --e-global-typography-74d688f-font-size );line-height:var( --e-global-typography-74d688f-line-height );}.elementor-1210 .elementor-element.elementor-element-0a8af6b{--gap:0px 10px;--row-gap:0px;--column-gap:10px;}.elementor-1210 .elementor-element.elementor-element-63f4a74 .elementor-heading-title{font-size:var( --e-global-typography-74d688f-font-size );line-height:var( --e-global-typography-74d688f-line-height );}.elementor-1210 .elementor-element.elementor-element-54c1327 .elementor-heading-title{font-size:var( --e-global-typography-74d688f-font-size );line-height:var( --e-global-typography-74d688f-line-height );}}\/* Start custom CSS for image, class: .elementor-element-9ce683f *\/.elementor-1210 .elementor-element.elementor-element-9ce683f a {\n    width: 100%;\n}\/* End custom CSS *\/\n\/* Start custom CSS for container, class: .elementor-element-237f3e9 *\/.elementor-1210 .elementor-element.elementor-element-237f3e9 {\n    height: 100%;\n}\/* End custom CSS *\/<\/style>\t\t<div data-elementor-type=\"loop-item\" data-elementor-id=\"1210\" class=\"elementor elementor-1210 e-loop-item e-loop-item-34919 post-34919 profil type-profil status-publish has-post-thumbnail hentry oddeleni-metabolomics oddeleni-translational-metabolism typ-pozice-vedouci-oddeleni ustav-fgu\" data-elementor-post-type=\"elementor_library\" data-custom-edit-handle=\"1\">\n\t\t\t<div class=\"elementor-element elementor-element-237f3e9 e-con-full e-flex e-con e-child\" data-id=\"237f3e9\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-9ce683f elementor-widget__width-initial elementor-widget elementor-widget-image\" data-id=\"9ce683f\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/fgu.cas.cz\/en\/profil\/doc-ing-tomas-cajka-ph-d\/\">\n\t\t\t\t\t\t\t<img decoding=\"async\" width=\"150\" height=\"150\" src=\"https:\/\/fgu.cas.cz\/wp-content\/uploads\/2024\/07\/tomas-cajka2-150x150.jpg\" class=\"attachment-thumbnail size-thumbnail wp-image-21667\" alt=\"-\" title=\"\">\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-0040c42 e-flex e-con-boxed e-con e-child\" data-id=\"0040c42\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-7229714 e-con-full e-flex e-con e-child\" data-id=\"7229714\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-d364753 elementor-widget__width-inherit elementor-widget elementor-widget-heading\" data-id=\"d364753\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h6 class=\"elementor-heading-title elementor-size-default\"><a href=\"https:\/\/fgu.cas.cz\/en\/profil\/doc-ing-tomas-cajka-ph-d\/\">Tom\u00e1\u0161 \u010cajka, Assoc. Prof.  M.Sc., Ph.D.<\/a><\/h6>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-ad7a981 position-info elementor-widget elementor-widget-heading\" data-id=\"ad7a981\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<span class=\"elementor-heading-title elementor-size-default\">Head of lab.; Senior research scientist<\/span>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-0a8af6b e-con-full contact-info e-flex e-con e-child\" data-id=\"0a8af6b\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-63f4a74 elementor-widget elementor-widget-heading\" data-id=\"63f4a74\" data-element_type=\"widget\" id=\"phone-orefix\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<span class=\"elementor-heading-title elementor-size-default\">Tel: 2187<\/span>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-54c1327 elementor-widget elementor-widget-heading\" data-id=\"54c1327\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<span class=\"elementor-heading-title elementor-size-default\">Email: tomas.cajka@fgu.cas.cz<\/span>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-5d12a6a e-con-full e-flex e-con e-child\" data-id=\"5d12a6a\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-82a6b01 dual__bold elementor-widget elementor-widget-heading\" data-id=\"82a6b01\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">Deputy Head of Laboratory<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2d27c7e elementor-grid-2 elementor-grid-tablet-2 elementor-grid-mobile-1 elementor-widget elementor-widget-loop-grid\" data-id=\"2d27c7e\" data-element_type=\"widget\" data-settings=\"{&quot;template_id&quot;:1210,&quot;columns&quot;:2,&quot;row_gap&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:20,&quot;sizes&quot;:[]},&quot;columns_tablet&quot;:2,&quot;row_gap_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:10,&quot;sizes&quot;:[]},&quot;_skin&quot;:&quot;post&quot;,&quot;columns_mobile&quot;:&quot;1&quot;,&quot;edit_handle_selector&quot;:&quot;[data-elementor-type=\\&quot;loop-item\\&quot;]&quot;,&quot;row_gap_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]}}\" data-widget_type=\"loop-grid.post\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-loop-container elementor-grid\" role=\"list\">\n\t\t\t\t<div data-elementor-type=\"loop-item\" data-elementor-id=\"1210\" class=\"elementor elementor-1210 e-loop-item e-loop-item-35244 post-35244 profil type-profil status-publish has-post-thumbnail hentry oddeleni-translational-metabolism typ-pozice-zastupce-vedouciho ustav-fgu\" data-elementor-post-type=\"elementor_library\" data-custom-edit-handle=\"1\">\n\t\t\t<div class=\"elementor-element elementor-element-237f3e9 e-con-full e-flex e-con e-child\" data-id=\"237f3e9\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-9ce683f elementor-widget__width-initial elementor-widget elementor-widget-image\" data-id=\"9ce683f\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/fgu.cas.cz\/en\/profil\/mgr-adam-eckhardt-ph-d\/\">\n\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"150\" height=\"150\" src=\"https:\/\/fgu.cas.cz\/wp-content\/uploads\/2024\/07\/default-people-150x150.png\" class=\"attachment-thumbnail size-thumbnail wp-image-4889\" alt=\"-\" srcset=\"https:\/\/fgu.cas.cz\/wp-content\/uploads\/2024\/07\/default-people-150x150.png 150w, https:\/\/fgu.cas.cz\/wp-content\/uploads\/2024\/07\/default-people-300x300.png 300w, https:\/\/fgu.cas.cz\/wp-content\/uploads\/2024\/07\/default-people-768x768.png 768w, https:\/\/fgu.cas.cz\/wp-content\/uploads\/2024\/07\/default-people.png 904w\" sizes=\"(max-width: 150px) 100vw, 150px\" title=\"\">\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-0040c42 e-flex e-con-boxed e-con e-child\" data-id=\"0040c42\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-7229714 e-con-full e-flex e-con e-child\" data-id=\"7229714\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-d364753 elementor-widget__width-inherit elementor-widget elementor-widget-heading\" data-id=\"d364753\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h6 class=\"elementor-heading-title elementor-size-default\"><a href=\"https:\/\/fgu.cas.cz\/en\/profil\/mgr-adam-eckhardt-ph-d\/\">Adam Eckhardt, M.Sc., Ph.D.<\/a><\/h6>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-ad7a981 position-info elementor-widget elementor-widget-heading\" data-id=\"ad7a981\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<span class=\"elementor-heading-title elementor-size-default\">Deputy head of lab.; Research Scientist<\/span>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-0a8af6b e-con-full contact-info e-flex e-con e-child\" data-id=\"0a8af6b\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-63f4a74 elementor-widget elementor-widget-heading\" data-id=\"63f4a74\" data-element_type=\"widget\" id=\"phone-orefix\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<span class=\"elementor-heading-title elementor-size-default\">Tel: 2127<\/span>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-54c1327 elementor-widget elementor-widget-heading\" data-id=\"54c1327\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<span class=\"elementor-heading-title elementor-size-default\">Email: adam.eckhardt@fgu.cas.cz<\/span>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-2b72290 e-con-full e-flex e-con e-child\" data-id=\"2b72290\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-26b7ec4 dual__bold elementor-widget elementor-widget-heading\" data-id=\"26b7ec4\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">Laboratory staff<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-28d15e4 elementor-grid-2 elementor-grid-tablet-2 elementor-grid-mobile-1 elementor-widget elementor-widget-loop-grid\" data-id=\"28d15e4\" data-element_type=\"widget\" data-settings=\"{&quot;template_id&quot;:1210,&quot;columns&quot;:2,&quot;row_gap&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:20,&quot;sizes&quot;:[]},&quot;columns_tablet&quot;:2,&quot;row_gap_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:10,&quot;sizes&quot;:[]},&quot;_skin&quot;:&quot;post&quot;,&quot;columns_mobile&quot;:&quot;1&quot;,&quot;edit_handle_selector&quot;:&quot;[data-elementor-type=\\&quot;loop-item\\&quot;]&quot;,&quot;row_gap_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]}}\" data-widget_type=\"loop-grid.post\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-loop-container elementor-grid\" role=\"list\">\n\t\t\t\t<div data-elementor-type=\"loop-item\" data-elementor-id=\"1210\" class=\"elementor elementor-1210 e-loop-item e-loop-item-35576 post-35576 profil type-profil status-publish has-post-thumbnail hentry oddeleni-translational-metabolism ustav-fgu\" data-elementor-post-type=\"elementor_library\" data-custom-edit-handle=\"1\">\n\t\t\t<div class=\"elementor-element elementor-element-237f3e9 e-con-full e-flex e-con e-child\" data-id=\"237f3e9\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-9ce683f elementor-widget__width-initial elementor-widget elementor-widget-image\" data-id=\"9ce683f\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/fgu.cas.cz\/en\/profil\/mgr-veronika-hola\/\">\n\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"150\" height=\"150\" src=\"https:\/\/fgu.cas.cz\/wp-content\/uploads\/2024\/07\/default-people-150x150.png\" class=\"attachment-thumbnail size-thumbnail wp-image-4889\" alt=\"-\" srcset=\"https:\/\/fgu.cas.cz\/wp-content\/uploads\/2024\/07\/default-people-150x150.png 150w, https:\/\/fgu.cas.cz\/wp-content\/uploads\/2024\/07\/default-people-300x300.png 300w, https:\/\/fgu.cas.cz\/wp-content\/uploads\/2024\/07\/default-people-768x768.png 768w, https:\/\/fgu.cas.cz\/wp-content\/uploads\/2024\/07\/default-people.png 904w\" sizes=\"(max-width: 150px) 100vw, 150px\" title=\"\">\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-0040c42 e-flex e-con-boxed e-con e-child\" data-id=\"0040c42\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-7229714 e-con-full e-flex e-con e-child\" data-id=\"7229714\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-d364753 elementor-widget__width-inherit elementor-widget elementor-widget-heading\" data-id=\"d364753\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h6 class=\"elementor-heading-title elementor-size-default\"><a href=\"https:\/\/fgu.cas.cz\/en\/profil\/mgr-veronika-hola\/\">Veronika Hol\u00e1, M.Sc.<\/a><\/h6>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-ad7a981 position-info elementor-widget elementor-widget-heading\" data-id=\"ad7a981\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<span class=\"elementor-heading-title elementor-size-default\">Research Specialist<\/span>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-0a8af6b e-con-full contact-info e-flex e-con e-child\" data-id=\"0a8af6b\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-63f4a74 elementor-widget elementor-widget-heading\" data-id=\"63f4a74\" data-element_type=\"widget\" id=\"phone-orefix\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<span class=\"elementor-heading-title elementor-size-default\">Tel: 2022<\/span>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-54c1327 elementor-widget elementor-widget-heading\" data-id=\"54c1327\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<span class=\"elementor-heading-title elementor-size-default\">Email: veronika.hola@fgu.cas.cz<\/span>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div data-elementor-type=\"loop-item\" data-elementor-id=\"1210\" class=\"elementor elementor-1210 e-loop-item e-loop-item-35314 post-35314 profil type-profil status-publish has-post-thumbnail hentry oddeleni-translational-metabolism ustav-fgu\" data-elementor-post-type=\"elementor_library\" data-custom-edit-handle=\"1\">\n\t\t\t<div class=\"elementor-element elementor-element-237f3e9 e-con-full e-flex e-con e-child\" data-id=\"237f3e9\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-9ce683f elementor-widget__width-initial elementor-widget elementor-widget-image\" data-id=\"9ce683f\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/fgu.cas.cz\/en\/profil\/mgr-armenuhi-kirakosjanova\/\">\n\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"150\" height=\"150\" src=\"https:\/\/fgu.cas.cz\/wp-content\/uploads\/2024\/07\/default-people-150x150.png\" class=\"attachment-thumbnail size-thumbnail wp-image-4889\" alt=\"-\" srcset=\"https:\/\/fgu.cas.cz\/wp-content\/uploads\/2024\/07\/default-people-150x150.png 150w, https:\/\/fgu.cas.cz\/wp-content\/uploads\/2024\/07\/default-people-300x300.png 300w, https:\/\/fgu.cas.cz\/wp-content\/uploads\/2024\/07\/default-people-768x768.png 768w, https:\/\/fgu.cas.cz\/wp-content\/uploads\/2024\/07\/default-people.png 904w\" sizes=\"(max-width: 150px) 100vw, 150px\" title=\"\">\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-0040c42 e-flex e-con-boxed e-con e-child\" data-id=\"0040c42\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-7229714 e-con-full e-flex e-con e-child\" data-id=\"7229714\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-d364753 elementor-widget__width-inherit elementor-widget elementor-widget-heading\" data-id=\"d364753\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h6 class=\"elementor-heading-title elementor-size-default\"><a href=\"https:\/\/fgu.cas.cz\/en\/profil\/mgr-armenuhi-kirakosjanova\/\">Armenuhi Kirakosjanov\u00e1, M.Sc.<\/a><\/h6>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-ad7a981 position-info elementor-widget elementor-widget-heading\" data-id=\"ad7a981\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<span class=\"elementor-heading-title elementor-size-default\">Research Specialist<\/span>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-0a8af6b e-con-full contact-info e-flex e-con e-child\" data-id=\"0a8af6b\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-63f4a74 elementor-widget elementor-widget-heading\" data-id=\"63f4a74\" data-element_type=\"widget\" id=\"phone-orefix\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<span class=\"elementor-heading-title elementor-size-default\">Tel: 2103<\/span>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-54c1327 elementor-widget elementor-widget-heading\" data-id=\"54c1327\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<span class=\"elementor-heading-title elementor-size-default\">Email: armenuhi.kirakosjanova@fgu.cas.cz<\/span>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div data-elementor-type=\"loop-item\" data-elementor-id=\"1210\" class=\"elementor elementor-1210 e-loop-item e-loop-item-36006 post-36006 profil type-profil status-publish has-post-thumbnail hentry oddeleni-translational-metabolism ustav-fgu\" data-elementor-post-type=\"elementor_library\" data-custom-edit-handle=\"1\">\n\t\t\t<div class=\"elementor-element elementor-element-237f3e9 e-con-full e-flex e-con e-child\" data-id=\"237f3e9\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-9ce683f elementor-widget__width-initial elementor-widget elementor-widget-image\" data-id=\"9ce683f\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/fgu.cas.cz\/en\/profil\/rndr-lucie-kulhava-ph-d\/\">\n\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"150\" height=\"150\" src=\"https:\/\/fgu.cas.cz\/wp-content\/uploads\/2024\/07\/default-people-150x150.png\" class=\"attachment-thumbnail size-thumbnail wp-image-4889\" alt=\"-\" srcset=\"https:\/\/fgu.cas.cz\/wp-content\/uploads\/2024\/07\/default-people-150x150.png 150w, https:\/\/fgu.cas.cz\/wp-content\/uploads\/2024\/07\/default-people-300x300.png 300w, https:\/\/fgu.cas.cz\/wp-content\/uploads\/2024\/07\/default-people-768x768.png 768w, https:\/\/fgu.cas.cz\/wp-content\/uploads\/2024\/07\/default-people.png 904w\" sizes=\"(max-width: 150px) 100vw, 150px\" title=\"\">\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-0040c42 e-flex e-con-boxed e-con e-child\" data-id=\"0040c42\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-7229714 e-con-full e-flex e-con e-child\" data-id=\"7229714\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-d364753 elementor-widget__width-inherit elementor-widget elementor-widget-heading\" data-id=\"d364753\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h6 class=\"elementor-heading-title elementor-size-default\"><a href=\"https:\/\/fgu.cas.cz\/en\/profil\/rndr-lucie-kulhava-ph-d\/\">Lucie Rudl Kulhav\u00e1, D.Sc., Ph.D.<\/a><\/h6>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-ad7a981 position-info elementor-widget elementor-widget-heading\" data-id=\"ad7a981\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<span class=\"elementor-heading-title elementor-size-default\">Postdoctoral researcher<\/span>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-0a8af6b e-con-full contact-info e-flex e-con e-child\" data-id=\"0a8af6b\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-63f4a74 elementor-widget elementor-widget-heading\" data-id=\"63f4a74\" data-element_type=\"widget\" id=\"phone-orefix\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<span class=\"elementor-heading-title elementor-size-default\">Tel: 2422<\/span>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-54c1327 elementor-widget elementor-widget-heading\" data-id=\"54c1327\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<span class=\"elementor-heading-title elementor-size-default\">Email: lucie.kulhava@fgu.cas.cz<\/span>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div data-elementor-type=\"loop-item\" data-elementor-id=\"1210\" class=\"elementor elementor-1210 e-loop-item e-loop-item-35117 post-35117 profil type-profil status-publish has-post-thumbnail hentry oddeleni-translational-metabolism ustav-fgu\" data-elementor-post-type=\"elementor_library\" data-custom-edit-handle=\"1\">\n\t\t\t<div class=\"elementor-element elementor-element-237f3e9 e-con-full e-flex e-con e-child\" data-id=\"237f3e9\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-9ce683f elementor-widget__width-initial elementor-widget elementor-widget-image\" data-id=\"9ce683f\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/fgu.cas.cz\/en\/profil\/ing-stanislava-rakusanova\/\">\n\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"150\" height=\"150\" src=\"https:\/\/fgu.cas.cz\/wp-content\/uploads\/2024\/07\/default-people-150x150.png\" class=\"attachment-thumbnail size-thumbnail wp-image-4889\" alt=\"-\" srcset=\"https:\/\/fgu.cas.cz\/wp-content\/uploads\/2024\/07\/default-people-150x150.png 150w, https:\/\/fgu.cas.cz\/wp-content\/uploads\/2024\/07\/default-people-300x300.png 300w, https:\/\/fgu.cas.cz\/wp-content\/uploads\/2024\/07\/default-people-768x768.png 768w, https:\/\/fgu.cas.cz\/wp-content\/uploads\/2024\/07\/default-people.png 904w\" sizes=\"(max-width: 150px) 100vw, 150px\" title=\"\">\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-0040c42 e-flex e-con-boxed e-con e-child\" data-id=\"0040c42\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-7229714 e-con-full e-flex e-con e-child\" data-id=\"7229714\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-d364753 elementor-widget__width-inherit elementor-widget elementor-widget-heading\" data-id=\"d364753\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h6 class=\"elementor-heading-title elementor-size-default\"><a href=\"https:\/\/fgu.cas.cz\/en\/profil\/ing-stanislava-rakusanova\/\">Stanislava Raku\u0161anov\u00e1, M.Sc.<\/a><\/h6>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-ad7a981 position-info elementor-widget elementor-widget-heading\" data-id=\"ad7a981\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<span class=\"elementor-heading-title elementor-size-default\">PhD student<\/span>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-0a8af6b e-con-full contact-info e-flex e-con e-child\" data-id=\"0a8af6b\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-63f4a74 elementor-widget elementor-widget-heading\" data-id=\"63f4a74\" data-element_type=\"widget\" id=\"phone-orefix\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<span class=\"elementor-heading-title elementor-size-default\">Tel: 2022<\/span>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-54c1327 elementor-widget elementor-widget-heading\" data-id=\"54c1327\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<span class=\"elementor-heading-title elementor-size-default\">Email: stanislava.rakusanova@fgu.cas.cz<\/span>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Content of this page Translational metabolism: Bridging the gap between research and medicine in metabolism\u00a0 About the Laboratory Our research involves applying mass spectrometry-based techniques to perform metabolomics, lipidomic and proteomic analysis of various biological samples. We develop and use\u00a0liquid chromatography\u2013mass spectrometry-based (LC\u2013MS) methods\u00a0for in-depth characterization and quantification of complex lipids (lipidome), polar metabolites (metabolome), [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":22745,"parent":24807,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"class_list":["post-24956","page","type-page","status-publish","has-post-thumbnail","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/fgu.cas.cz\/en\/wp-json\/wp\/v2\/pages\/24956","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/fgu.cas.cz\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/fgu.cas.cz\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/fgu.cas.cz\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/fgu.cas.cz\/en\/wp-json\/wp\/v2\/comments?post=24956"}],"version-history":[{"count":0,"href":"https:\/\/fgu.cas.cz\/en\/wp-json\/wp\/v2\/pages\/24956\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/fgu.cas.cz\/en\/wp-json\/wp\/v2\/pages\/24807"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/fgu.cas.cz\/en\/wp-json\/wp\/v2\/media\/22745"}],"wp:attachment":[{"href":"https:\/\/fgu.cas.cz\/en\/wp-json\/wp\/v2\/media?parent=24956"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}