{"id":27044,"date":"2024-08-06T12:08:05","date_gmt":"2024-08-06T10:08:05","guid":{"rendered":"https:\/\/fgu.antstudio.dev\/research-and-laboratories\/research\/vyzkumne-smery\/"},"modified":"2025-11-18T16:02:35","modified_gmt":"2025-11-18T15:02:35","slug":"research-topics","status":"publish","type":"page","link":"https:\/\/fgu.cas.cz\/en\/research-and-laboratories\/research\/research-topics\/","title":{"rendered":"Research topics"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"27044\" class=\"elementor elementor-27044 elementor-21386\" data-elementor-post-type=\"page\">\n\t\t\t\t<div class=\"elementor-element elementor-element-ecd1db9 e-flex e-con-boxed e-con e-parent\" data-id=\"ecd1db9\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-f7dcc7b e-con-full elementor-hidden-tablet elementor-hidden-mobile e-flex e-con e-child\" data-id=\"f7dcc7b\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-bbc0074 elementor-widget__width-initial elementor-widget elementor-widget-heading\" data-id=\"bbc0074\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h1 class=\"elementor-heading-title elementor-size-default\">Research topics<\/h1>\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-95fdb42 e-flex e-con-boxed e-con e-parent\" data-id=\"95fdb42\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-bb29f82 elementor-absolute elementor-hidden-tablet elementor-hidden-mobile elementor-widget elementor-widget-image\" data-id=\"bb29f82\" data-element_type=\"widget\" data-settings=\"{&quot;_position&quot;:&quot;absolute&quot;}\" data-widget_type=\"image.default\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"708\" height=\"789\" src=\"https:\/\/fgu.cas.cz\/wp-content\/uploads\/2025\/11\/bg-3.webp\" class=\"attachment-large size-large wp-image-51089\" alt=\"-\" srcset=\"https:\/\/fgu.cas.cz\/wp-content\/uploads\/2025\/11\/bg-3.webp 708w, https:\/\/fgu.cas.cz\/wp-content\/uploads\/2025\/11\/bg-3-269x300.webp 269w\" sizes=\"(max-width: 708px) 100vw, 708px\" title=\"\">\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-86b21d5 e-con-full elementor-hidden-tablet elementor-hidden-mobile e-flex e-con e-child\" data-id=\"86b21d5\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;,&quot;sticky&quot;:&quot;top&quot;,&quot;sticky_on&quot;:[&quot;desktop&quot;],&quot;sticky_offset&quot;:80,&quot;sticky_parent&quot;:&quot;yes&quot;,&quot;sticky_effects_offset&quot;:0,&quot;sticky_anchor_link_offset&quot;:0}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-157d325 elementor-widget elementor-widget-heading\" data-id=\"157d325\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">Content of this page\n<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5269f78 elementor-toc--content-ellipsis elementor-widget elementor-widget-table-of-contents\" data-id=\"5269f78\" data-element_type=\"widget\" data-settings=\"{&quot;headings_by_tags&quot;:[&quot;h2&quot;],&quot;exclude_headings_by_selector&quot;:[],&quot;marker_view&quot;:&quot;bullets&quot;,&quot;icon&quot;:{&quot;value&quot;:&quot;&quot;,&quot;library&quot;:&quot;&quot;},&quot;min_height&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:200,&quot;sizes&quot;:[]},&quot;no_headings_message&quot;:&quot;No headings were found on this page.&quot;,&quot;min_height_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;min_height_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]}}\" data-widget_type=\"table-of-contents.default\">\n\t\t\t\t\t\t\t\t\t<div id=\"elementor-toc__5269f78\" class=\"elementor-toc__body\">\n\t\t\t<div class=\"elementor-toc__spinner-container\">\n\t\t\t\t<i class=\"elementor-toc__spinner eicon-animation-spin eicon-loading\" aria-hidden=\"true\"><\/i>\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-c66d530 e-con-full e-flex e-con e-child\" data-id=\"c66d530\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-a0570c6 elementor-widget elementor-widget-image\" data-id=\"a0570c6\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"700\" height=\"239\" src=\"https:\/\/fgu.cas.cz\/wp-content\/uploads\/2024\/08\/d1hrmu3l2t27odx19luw.png\" class=\"attachment-1536x1536 size-1536x1536 wp-image-21246\" alt=\"-\" srcset=\"https:\/\/fgu.cas.cz\/wp-content\/uploads\/2024\/08\/d1hrmu3l2t27odx19luw.png 700w, https:\/\/fgu.cas.cz\/wp-content\/uploads\/2024\/08\/d1hrmu3l2t27odx19luw-300x102.png 300w\" sizes=\"(max-width: 700px) 100vw, 700px\" title=\"\">\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-23f5255 e-con-full e-flex e-con e-child\" data-id=\"23f5255\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-db3c64c elementor-widget elementor-widget-heading\" data-id=\"db3c64c\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">About research<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3f9b806 elementor-widget elementor-widget-text-editor\" data-id=\"3f9b806\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>Scientific laboratories are currently grouped according to their research interests.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-70ea44e e-grid e-con-full e-con e-child\" data-id=\"70ea44e\" data-element_type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-0ce52e3 e-con-full e-flex e-con e-child\" data-id=\"0ce52e3\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-1d5fddc dual__bold elementor-widget elementor-widget-heading\" data-id=\"1d5fddc\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\"><a href=\"#neurovedy\">NEUROSCIENCE<\/a><\/h4>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5e83455 elementor-widget elementor-widget-text-editor\" data-id=\"5e83455\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>Neuroscientific research covers a broad spectrum of problems ranging from the mechanisms of neurotransmitter release and actions of transmitters on their receptors to integrative functions of the central nervous system, such as memory, regulation of circadian rhythms and pathophysiological mechanisms of epilepsies.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-e0301e9 e-con-full e-flex e-con e-child\" data-id=\"e0301e9\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-7339c2b dual__bold elementor-widget elementor-widget-heading\" data-id=\"7339c2b\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\"><a href=\"#kardiofyziologie\">CARDIOVASCULAR PHYSIOLOGY\n\n<\/a><\/h4>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-73706a0 elementor-widget elementor-widget-text-editor\" data-id=\"73706a0\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>Research concerning the physiology and pathophysiology of the cardiovascular system focuses on the developmental aspects of cardiac contractile function, experimental hypertension and renovascular physiology. Special attention is being paid to the role of proteins and cell membranes.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-ab43080 e-con-full e-flex e-con e-child\" data-id=\"ab43080\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-7c0211c dual__bold elementor-widget elementor-widget-heading\" data-id=\"7c0211c\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\"><a href=\"#metabolismus\">METABOLISM\n<\/a><\/h4>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5092f3e elementor-widget elementor-widget-text-editor\" data-id=\"5092f3e\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>Research of metabolism covers problems related to cell metabolism, functions of mitochondria, membrane transport and signal transduction are investigated at both the cellular and intercellular level.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-a9f55a7 e-con-full e-flex e-con e-child\" data-id=\"a9f55a7\" data-element_type=\"container\" id=\"neurovedy\">\n\t\t\t\t<div class=\"elementor-element elementor-element-411f62d elementor-widget elementor-widget-heading\" data-id=\"411f62d\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Neuroscience<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-ea708ac elementor-widget elementor-widget-image\" data-id=\"ea708ac\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"700\" height=\"265\" src=\"https:\/\/fgu.cas.cz\/wp-content\/uploads\/2024\/08\/bv785uc1u5tryb8iws00.png\" class=\"attachment-1536x1536 size-1536x1536 wp-image-21273\" alt=\"-\" srcset=\"https:\/\/fgu.cas.cz\/wp-content\/uploads\/2024\/08\/bv785uc1u5tryb8iws00.png 700w, https:\/\/fgu.cas.cz\/wp-content\/uploads\/2024\/08\/bv785uc1u5tryb8iws00-300x114.png 300w\" sizes=\"(max-width: 700px) 100vw, 700px\" title=\"\">\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-fdb1482 elementor-widget elementor-widget-text-editor\" data-id=\"fdb1482\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>The research into the field of neuroscience at our institute covers many aspects of neural transmission, not only in a practical way, but also in a theoretical way using computer simulations and modelling.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b9d8b60 elementor-widget elementor-widget-text-editor\" data-id=\"b9d8b60\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>We investigate in detail the biochemical principles of signal transmission from one cell to another, i.e. mechanisms of neurotransmitter release and interactions between neurotransmitters and their receptors (e.g. muscarinic acetylcholine receptors, purinergic P2X receptors, vanilloid TRPV receptors). On the other hand, we study also integrative functions of the central nervous system that include:<\/p><ul><li>cognitive functions (memory, space orientation, or learning),<\/li><li>regulation of circadian rhythms (i.e. processes repeated rhythmically during the 24-hour period),<\/li><li>mechanisms of drug addictions, chronic pain, or epilepsy.<\/li><\/ul><p><br \/>Among other diseases of nervous system, our research focuses also on Alzheimer\u2019s disease or schizophrenia.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-5cc0023 e-con-full e-flex e-con e-child\" data-id=\"5cc0023\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-c417324 dual__bold elementor-widget elementor-widget-heading\" data-id=\"c417324\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">Scientific laboratories<\/h4>\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-e5c8562 e-grid e-con-full e-con e-child\" data-id=\"e5c8562\" data-element_type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-7fe4b5c e-con-full e-flex e-con e-child\" data-id=\"7fe4b5c\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-7b8487c dual__bold elementor-widget elementor-widget-heading\" data-id=\"7b8487c\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h5 class=\"elementor-heading-title elementor-size-default\"><a href=\"https:\/\/fgu.cas.cz\/en\/research-and-laboratories\/research-departments\/laboratory-of-biological-rhythms\/\">Laboratory of Biological Rhythms\n<\/a><\/h5>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-4fba97e e-con-full e-flex e-con e-child\" data-id=\"4fba97e\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-b43e370 dual__bold elementor-widget elementor-widget-heading\" data-id=\"b43e370\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h5 class=\"elementor-heading-title elementor-size-default\"><a href=\"https:\/\/fgu.cas.cz\/en\/research-and-laboratories\/research-departments\/laboratory-of-neurochemistry\/\">Laboratory of Neurochemistry\n<\/a><\/h5>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-f7adc2f e-con-full e-flex e-con e-child\" data-id=\"f7adc2f\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-e07d700 dual__bold elementor-widget elementor-widget-heading\" data-id=\"e07d700\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h5 class=\"elementor-heading-title elementor-size-default\"><a href=\"https:\/\/fgu.cas.cz\/en\/research-and-laboratories\/research-departments\/laboratory-of-cellular-neurophysiology\/\">Laboratory of Cellular Neurophysiology\n<\/a><\/h5>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-04837ac e-con-full e-flex e-con e-child\" data-id=\"04837ac\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-a849db8 dual__bold elementor-widget elementor-widget-heading\" data-id=\"a849db8\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h5 class=\"elementor-heading-title elementor-size-default\"><a href=\"https:\/\/fgu.cas.cz\/en\/research-and-laboratories\/research-departments\/laboratory-of-computational-neuroscience\/\">Laboratory of Computational Neuroscience\n<\/a><\/h5>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-70ec11d e-con-full e-flex e-con e-child\" data-id=\"70ec11d\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-f3e1bee dual__bold elementor-widget elementor-widget-heading\" data-id=\"f3e1bee\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h5 class=\"elementor-heading-title elementor-size-default\"><a href=\"https:\/\/fgu.cas.cz\/en\/research-and-laboratories\/research-departments\/laboratory-of-molecular-neurobiology\/\">Laboratory of Molecular Neurobiology<\/a><\/h5>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-47ce704 e-con-full e-flex e-con e-child\" data-id=\"47ce704\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-a0804fd dual__bold elementor-widget elementor-widget-heading\" data-id=\"a0804fd\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h5 class=\"elementor-heading-title elementor-size-default\"><a href=\"https:\/\/fgu.cas.cz\/en\/research-and-laboratories\/research-departments\/laboratory-of-developmental-epileptology\/\">Laboratory of Developmental Epileptology<\/a><\/h5>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-7e1c413 e-con-full e-flex e-con e-child\" data-id=\"7e1c413\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-1c41ebf dual__bold elementor-widget elementor-widget-heading\" data-id=\"1c41ebf\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h5 class=\"elementor-heading-title elementor-size-default\"><a href=\"https:\/\/fgu.cas.cz\/en\/research-and-laboratories\/research-departments\/laboratory-of-neurophysiology-of-memory\/\">Laboratory of Neurophysiology of Memory\n<\/a><\/h5>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-00fac0d e-con-full e-flex e-con e-child\" data-id=\"00fac0d\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-79a7421 dual__bold elementor-widget elementor-widget-heading\" data-id=\"79a7421\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h5 class=\"elementor-heading-title elementor-size-default\"><a href=\"https:\/\/fgu.cas.cz\/en\/research-and-laboratories\/research-departments\/laboratory-of-pain-research\/\">Laboratory of Pain Research\n<\/a><\/h5>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-087c3a6 e-con-full e-flex e-con e-child\" data-id=\"087c3a6\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-eda5951 dual__bold elementor-widget elementor-widget-heading\" data-id=\"eda5951\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h5 class=\"elementor-heading-title elementor-size-default\"><a href=\"https:\/\/fgu.cas.cz\/en\/research-and-laboratories\/research-departments\/laboratory-of-cholinergic-signaling\/\">Laboratory of Cholinergic Signaling\n<\/a><\/h5>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-fb7062c e-con-full e-flex e-con e-child\" data-id=\"fb7062c\" data-element_type=\"container\" id=\"kardiofyziologie\">\n\t\t\t\t<div class=\"elementor-element elementor-element-ab5c62c elementor-widget elementor-widget-heading\" data-id=\"ab5c62c\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Cardiovascular Physiology\n<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-14698e8 elementor-widget elementor-widget-image\" data-id=\"14698e8\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"1000\" height=\"504\" src=\"https:\/\/fgu.cas.cz\/wp-content\/uploads\/2024\/08\/kardiovaskularni-fyziologie.jpg\" class=\"attachment-1536x1536 size-1536x1536 wp-image-21382\" alt=\"-\" srcset=\"https:\/\/fgu.cas.cz\/wp-content\/uploads\/2024\/08\/kardiovaskularni-fyziologie.jpg 1000w, https:\/\/fgu.cas.cz\/wp-content\/uploads\/2024\/08\/kardiovaskularni-fyziologie-300x151.jpg 300w, https:\/\/fgu.cas.cz\/wp-content\/uploads\/2024\/08\/kardiovaskularni-fyziologie-768x387.jpg 768w\" sizes=\"(max-width: 1000px) 100vw, 1000px\" title=\"\">\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-15ce4f5 elementor-widget elementor-widget-text-editor\" data-id=\"15ce4f5\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>Cardiovascular diseases (hypertension, cardiac arrhythmias, or heart failure) have been recently the most frequent cause of death in the developed countries. The older the Western population has got, the more frequent incidence of cardiovascular diseases there has been.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-d5151f6 elementor-widget elementor-widget-text-editor\" data-id=\"d5151f6\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>The explanation of physiological as well as pathophysiological processes within the cardiovascular system therefore represents an important goal of our research.<\/p><p>We study:<\/p><ul><li>mechanisms of development and prevention of ischemic heart disease that leads to heart attack,<\/li><li>developmental aspects of heart contractions and their role in heart arrhythmias,<\/li><li>mechanisms of vascular contraction and their use for treatment of hypertension.<\/li><\/ul><p><br \/>In addition, we contribute to the development of biomaterials that would be suitable for synthetic vascular substitutes. We also look for genes, whose defects or modifications can underlie some of the cardiovascular diseases.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-69a121a e-con-full e-flex e-con e-child\" data-id=\"69a121a\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-88a6b66 dual__bold elementor-widget elementor-widget-heading\" data-id=\"88a6b66\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">Scientific laboratories<\/h4>\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-67128b0 e-grid e-con-full e-con e-child\" data-id=\"67128b0\" data-element_type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-b2bc88b e-con-full e-flex e-con e-child\" data-id=\"b2bc88b\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-7381054 dual__bold elementor-widget elementor-widget-heading\" data-id=\"7381054\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h5 class=\"elementor-heading-title elementor-size-default\"><a href=\"https:\/\/fgu.cas.cz\/en\/research-and-laboratories\/research-departments\/laboratory-of-biomaterials-and-tissue-engineering\/\">Laboratory of Biomaterials and Tissue Engineering<\/a><\/h5>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-aae0bed e-con-full e-flex e-con e-child\" data-id=\"aae0bed\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-53353f1 dual__bold elementor-widget elementor-widget-heading\" data-id=\"53353f1\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h5 class=\"elementor-heading-title elementor-size-default\"><a href=\"https:\/\/fgu.cas.cz\/en\/research-and-laboratories\/research-departments\/laboratory-of-genetics-of-model-diseases\/\">Laboratory of Genetics of Model Diseases<\/a><\/h5>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-e9656e2 e-con-full e-flex e-con e-child\" data-id=\"e9656e2\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-3dd5d30 dual__bold elementor-widget elementor-widget-heading\" data-id=\"3dd5d30\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h5 class=\"elementor-heading-title elementor-size-default\"><a href=\"https:\/\/fgu.cas.cz\/en\/research-and-laboratories\/research-departments\/laboratory-of-experimental-hypertension\/\">Laboratory of Experimental Hypertension<\/a><\/h5>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-6c1ebf7 e-con-full e-flex e-con e-child\" data-id=\"6c1ebf7\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-68ad847 dual__bold elementor-widget elementor-widget-heading\" data-id=\"68ad847\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h5 class=\"elementor-heading-title elementor-size-default\"><a href=\"https:\/\/fgu.cas.cz\/en\/research-and-laboratories\/research-departments\/laboratory-of-developmental-cardiology\/\">Laboratory of Developmental Cardiology<\/a><\/h5>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-914a52a e-con-full e-flex e-con e-child\" data-id=\"914a52a\" data-element_type=\"container\" id=\"metabolismus\">\n\t\t\t\t<div class=\"elementor-element elementor-element-b904a53 elementor-widget elementor-widget-heading\" data-id=\"b904a53\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Metabolism<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-88f6594 elementor-widget elementor-widget-image\" data-id=\"88f6594\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"700\" height=\"204\" src=\"https:\/\/fgu.cas.cz\/wp-content\/uploads\/2024\/08\/szq6zpao24s6idodforj.jpg\" class=\"attachment-1536x1536 size-1536x1536 wp-image-21364\" alt=\"-\" srcset=\"https:\/\/fgu.cas.cz\/wp-content\/uploads\/2024\/08\/szq6zpao24s6idodforj.jpg 700w, https:\/\/fgu.cas.cz\/wp-content\/uploads\/2024\/08\/szq6zpao24s6idodforj-300x87.jpg 300w\" sizes=\"(max-width: 700px) 100vw, 700px\" title=\"\">\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1985fa5 elementor-widget elementor-widget-text-editor\" data-id=\"1985fa5\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>We study metabolic processes and signal transduction also at the cellular and molecular level.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-31585b4 elementor-widget elementor-widget-text-editor\" data-id=\"31585b4\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>Concerning energy metabolism, we study mitochondria under both physiological and pathophysiological conditions. We look into the mitochondrial structure and function at mitochondrial defects as well as other metabolic, cardiovascular, and neurophysiological diseases.<\/p><p>Studying various models of mammalian and yeast cells, we investigate transport systems in cell membranes that also play an essential role in cell metabolism.<\/p><p>In the field of signal transduction, we try to explain molecular principles of neural transmission under both physiological and pathophysiological conditions.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-6d8a8c8 e-con-full e-flex e-con e-child\" data-id=\"6d8a8c8\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-df858f0 dual__bold elementor-widget elementor-widget-heading\" data-id=\"df858f0\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">Scientific laboratories<\/h4>\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-36be8b0 e-grid e-con-full e-con e-child\" data-id=\"36be8b0\" data-element_type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-68a7210 e-con-full e-flex e-con e-child\" data-id=\"68a7210\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-429c663 dual__bold elementor-widget elementor-widget-heading\" data-id=\"429c663\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h5 class=\"elementor-heading-title elementor-size-default\"><a href=\"https:\/\/fgu.cas.cz\/en\/research-and-laboratories\/research-departments\/laboratory-of-bioenergetics\/\">Laboratory of Bioenergetics<\/a><\/h5>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-e935618 e-con-full e-flex e-con e-child\" data-id=\"e935618\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-ef063a8 dual__bold elementor-widget elementor-widget-heading\" data-id=\"ef063a8\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h5 class=\"elementor-heading-title elementor-size-default\"><a href=\"https:\/\/fgu.cas.cz\/en\/research-and-laboratories\/research-departments\/laboratory-of-mitochondrial-physiology\/\">Laboratory of Mitochondrial Physiology<\/a><\/h5>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-a912cf5 e-con-full e-flex e-con e-child\" data-id=\"a912cf5\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-fbcf8d7 dual__bold elementor-widget elementor-widget-heading\" data-id=\"fbcf8d7\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h5 class=\"elementor-heading-title elementor-size-default\"><a href=\"https:\/\/fgu.cas.cz\/en\/research-and-laboratories\/research-departments\/laboratory-of-adipose-tissue-biology\/\">Laboratory of Adipose Tissue Biology<\/a><\/h5>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-f6338b4 e-con-full e-flex e-con e-child\" data-id=\"f6338b4\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-251af65 dual__bold elementor-widget elementor-widget-heading\" data-id=\"251af65\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h5 class=\"elementor-heading-title elementor-size-default\"><a href=\"https:\/\/fgu.cas.cz\/en\/research-and-laboratories\/research-departments\/laboratory-of-molecular-physiology-of-bone\/\">Laboratory of Molecular Physiology of Bone<\/a><\/h5>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-64e2e6d e-con-full e-flex e-con e-child\" data-id=\"64e2e6d\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-b972450 dual__bold elementor-widget elementor-widget-heading\" data-id=\"b972450\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h5 class=\"elementor-heading-title elementor-size-default\"><a href=\"https:\/\/fgu.cas.cz\/en\/research-and-laboratories\/research-departments\/laboratory-of-metabolism-of-bioactive-lipids\/\">Laboratory of Metabolism of Bioactive Lipids<\/a><\/h5>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-dda8bf2 e-con-full e-flex e-con e-child\" data-id=\"dda8bf2\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-c60affd dual__bold elementor-widget elementor-widget-heading\" data-id=\"c60affd\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h5 class=\"elementor-heading-title elementor-size-default\"><a href=\"https:\/\/fgu.cas.cz\/en\/research-and-laboratories\/research-departments\/laboratory-of-structural-biology-of-signaling-proteins\/\">Laboratory of Structural Biology of Signaling Proteins\n<\/a><\/h5>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-d3215ce e-con-full e-flex e-con e-child\" data-id=\"d3215ce\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-448dbc8 dual__bold elementor-widget elementor-widget-heading\" data-id=\"448dbc8\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h5 class=\"elementor-heading-title elementor-size-default\"><a href=\"https:\/\/fgu.cas.cz\/en\/research-and-laboratories\/research-departments\/laboratory-of-membrane-transport\/\">Laboratory of Membrane Transport\n<\/a><\/h5>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-7adb708 e-con-full e-flex e-con e-child\" data-id=\"7adb708\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-31c26fc dual__bold elementor-widget elementor-widget-heading\" data-id=\"31c26fc\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h5 class=\"elementor-heading-title elementor-size-default\"><a href=\"https:\/\/fgu.cas.cz\/en\/research-and-laboratories\/research-departments\/laboratory-of-translational-metabolism\/\">Laboratory of Translational Metabolism\n<\/a><\/h5>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-4d4dce5 e-con-full e-flex e-con e-child\" data-id=\"4d4dce5\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-742cb65 dual__bold elementor-widget elementor-widget-heading\" data-id=\"742cb65\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h5 class=\"elementor-heading-title elementor-size-default\"><a href=\"https:\/\/fgu.cas.cz\/en\/research-and-laboratories\/research-departments\/laboratory-of-pancreatic-islet-research\/\">Laboratory of Pancreatic Islet Research<\/a><\/h5>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Content of this page About research Scientific laboratories are currently grouped according to their research interests. NEUROSCIENCE Neuroscientific research covers a broad spectrum of problems ranging from the mechanisms of neurotransmitter release and actions of transmitters on their receptors to integrative functions of the central nervous system, such as memory, regulation of circadian rhythms and [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":55280,"parent":26020,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"class_list":["post-27044","page","type-page","status-publish","has-post-thumbnail","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/fgu.cas.cz\/en\/wp-json\/wp\/v2\/pages\/27044","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/fgu.cas.cz\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/fgu.cas.cz\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/fgu.cas.cz\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/fgu.cas.cz\/en\/wp-json\/wp\/v2\/comments?post=27044"}],"version-history":[{"count":0,"href":"https:\/\/fgu.cas.cz\/en\/wp-json\/wp\/v2\/pages\/27044\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/fgu.cas.cz\/en\/wp-json\/wp\/v2\/pages\/26020"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/fgu.cas.cz\/en\/wp-json\/wp\/v2\/media\/55280"}],"wp:attachment":[{"href":"https:\/\/fgu.cas.cz\/en\/wp-json\/wp\/v2\/media?parent=27044"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}