{"id":39848,"date":"2025-02-25T08:00:18","date_gmt":"2025-02-25T07:00:18","guid":{"rendered":"https:\/\/fgu.cas.cz\/?p=39848"},"modified":"2025-02-21T13:53:42","modified_gmt":"2025-02-21T12:53:42","slug":"press-release-mitochondrial-genes-are-also-responsible-for-the-development-of-insulin-resistance","status":"publish","type":"post","link":"https:\/\/fgu.cas.cz\/en\/2025\/02\/press-release-mitochondrial-genes-are-also-responsible-for-the-development-of-insulin-resistance\/","title":{"rendered":"Press release: Mitochondrial genes are responsible also for the development of insulin resistance"},"content":{"rendered":"<p>Obesity, high blood sugar or insulin resistance are among the most common symptoms of metabolic syndrome. However, its hereditary causes are not yet fully understood. Scientists from the Laboratory of Bioenergetics of the Institute of Physiology of the CAS and the <a href=\"https:\/\/cardia.ikem.cz\/en\/home\" target=\"_blank\" rel=\"noopener\">National Institute CarDia<\/a>\u00a0have found that DNA variability in mitochondria could play an important role in the development of metabolic syndrome symptoms.<\/p>\n<p><a href=\"https:\/\/fgu.cas.cz\/wp-content\/uploads\/2025\/02\/FGU_metabolicky-syndrom_250225_final.pdf\">Press release (in Czech)<\/a><\/p>\n<p>Reference: Pecina P., \u010cun\u00e1tov\u00e1 K., Kaplanov\u00e1 V., Puertas-Frias G., \u0160ilhav\u00fd J., Tauchmannov\u00e1 K., Vrback\u00fd M., \u010cajka T., Gahura O., Hlav\u00e1\u010dkov\u00e1 M., Str\u00e1neck\u00fd V., Kmoch S., Pravenec M., Hou\u0161t\u011bk J., Mr\u00e1\u010dek T., Pecinov\u00e1 A.: Haplotype variability in mitochondrial rRNA predisposes to metabolic syndrome. Communications Biology 7(1):1116 (2024). <a href=\"https:\/\/www.nature.com\/articles\/s42003-024-06819-w\" target=\"_blank\" rel=\"noopener\">DOI<\/a><\/p>\n<p><img decoding=\"async\" class=\"alignnone wp-image-38480\" src=\"https:\/\/fgu.cas.cz\/wp-content\/uploads\/2025\/01\/cardia-cz-300x142.png\" alt=\"-\" width=\"82\" height=\"39\" title=\"\" srcset=\"https:\/\/fgu.cas.cz\/wp-content\/uploads\/2025\/01\/cardia-cz-300x142.png 300w, https:\/\/fgu.cas.cz\/wp-content\/uploads\/2025\/01\/cardia-cz.png 549w\" sizes=\"(max-width: 82px) 100vw, 82px\" \/> \u00a0<img decoding=\"async\" class=\"alignnone size-medium wp-image-39252\" src=\"https:\/\/fgu.cas.cz\/wp-content\/uploads\/2025\/01\/3logo-ec-npo-msmt-cz-1-300x53.jpg\" alt=\"-\" width=\"300\" height=\"53\" title=\"\" srcset=\"https:\/\/fgu.cas.cz\/wp-content\/uploads\/2025\/01\/3logo-ec-npo-msmt-cz-1-300x53.jpg 300w, https:\/\/fgu.cas.cz\/wp-content\/uploads\/2025\/01\/3logo-ec-npo-msmt-cz-1-1024x179.jpg 1024w, https:\/\/fgu.cas.cz\/wp-content\/uploads\/2025\/01\/3logo-ec-npo-msmt-cz-1-768x135.jpg 768w, https:\/\/fgu.cas.cz\/wp-content\/uploads\/2025\/01\/3logo-ec-npo-msmt-cz-1-1536x269.jpg 1536w, https:\/\/fgu.cas.cz\/wp-content\/uploads\/2025\/01\/3logo-ec-npo-msmt-cz-1-2048x359.jpg 2048w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Obesity, high blood sugar or insulin resistance are among the most common symptoms of metabolic syndrome. However, its hereditary causes are not yet fully understood. Scientists from the Laboratory of Bioenergetics of the Institute of Physiology of the CAS and the National Institute CarDia\u00a0have found that DNA variability in mitochondria could play an important role [&hellip;]<\/p>\n","protected":false},"author":5,"featured_media":39846,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"categories":[142,278],"tags":[],"class_list":["post-39848","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-for-media","category-popularization"],"acf":[],"_links":{"self":[{"href":"https:\/\/fgu.cas.cz\/en\/wp-json\/wp\/v2\/posts\/39848","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/fgu.cas.cz\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/fgu.cas.cz\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/fgu.cas.cz\/en\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/fgu.cas.cz\/en\/wp-json\/wp\/v2\/comments?post=39848"}],"version-history":[{"count":0,"href":"https:\/\/fgu.cas.cz\/en\/wp-json\/wp\/v2\/posts\/39848\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/fgu.cas.cz\/en\/wp-json\/wp\/v2\/media\/39846"}],"wp:attachment":[{"href":"https:\/\/fgu.cas.cz\/en\/wp-json\/wp\/v2\/media?parent=39848"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/fgu.cas.cz\/en\/wp-json\/wp\/v2\/categories?post=39848"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/fgu.cas.cz\/en\/wp-json\/wp\/v2\/tags?post=39848"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}