{"id":6956,"date":"2021-01-15T00:00:00","date_gmt":"2021-01-14T23:00:00","guid":{"rendered":"https:\/\/fgu.antstudio.dev\/2021\/01\/tomas-cajka-is-a-co-author-of-the-unique-software-for-analyses-of-complex-lipids-in-biological-samples\/"},"modified":"2024-07-23T11:38:52","modified_gmt":"2024-07-23T09:38:52","slug":"tomas-cajka-is-a-co-author-of-the-unique-software-for-analyses-of-complex-lipids-in-biological-samples","status":"publish","type":"post","link":"https:\/\/fgu.cas.cz\/en\/2021\/01\/tomas-cajka-is-a-co-author-of-the-unique-software-for-analyses-of-complex-lipids-in-biological-samples\/","title":{"rendered":"Tom\u00e1\u0161 Cajka is a co-author of the unique software for analyses of complex lipids in biological samples"},"content":{"rendered":"

Processing of instrumental files acquired during untargeted metabolomics and lipidomics analyses represents a challenging task. It is estimated that only 20 percent of signals (features) collected during untargeted liquid chromatography\u2013mass spectrometry (LC\u2013MS) methods can be annotated. MS-DIAL represents user-friendly, open-access software for processing untargeted metabolomics and lipidomics instrumental files. The latest version contains an atlas (database) for 117 lipid subclasses with predicted retention times, tandem mass spectrometry spectra (MS\/MS), and collision cross sections (CCS) for annotation of complex lipids in biological samples. Using MS-DIAL 4, a higher number of annotated complex lipids in biological samples is achieved compared to other software programs in this field permitting more meaningful data interpretation.<\/p>\n

\"-\"<\/p>\n

H. Tsugawa, K. Ikeda, M. Takahashi, A. Satoh, Y. Mori, H. Uchino, N. Okahashi, Y. Yamada, I. Tada, P. Bonini, Y. Higashi, Y. Okazaki, Z. Zhou, Z.-J. Zhu, J. Koelmel, T. Cajka, O. Fiehn, K. Saito, M. Arita, M. Arita: A lipidome atlas in MS-DIAL 4. Nature Biotechnology 38 (2020) 1159\u20131163. IF = 36.558<\/strong> <\/span>DOI<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Processing of instrumental files acquired during untargeted metabolomics and lipidomics analyses represents a challenging task. It is estimated that only 20 percent of signals (features) collected during untargeted liquid chromatography\u2013mass spectrometry (LC\u2013MS) methods can be annotated. MS-DIAL represents user-friendly, open-access software for processing untargeted metabolomics and lipidomics instrumental files. The latest version contains an atlas […]<\/p>\n","protected":false},"author":1,"featured_media":6482,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"categories":[2],"tags":[],"class_list":["post-6956","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-other"],"acf":[],"_links":{"self":[{"href":"https:\/\/fgu.cas.cz\/en\/wp-json\/wp\/v2\/posts\/6956","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/fgu.cas.cz\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/fgu.cas.cz\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/fgu.cas.cz\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/fgu.cas.cz\/en\/wp-json\/wp\/v2\/comments?post=6956"}],"version-history":[{"count":0,"href":"https:\/\/fgu.cas.cz\/en\/wp-json\/wp\/v2\/posts\/6956\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/fgu.cas.cz\/en\/wp-json\/wp\/v2\/media\/6482"}],"wp:attachment":[{"href":"https:\/\/fgu.cas.cz\/en\/wp-json\/wp\/v2\/media?parent=6956"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/fgu.cas.cz\/en\/wp-json\/wp\/v2\/categories?post=6956"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/fgu.cas.cz\/en\/wp-json\/wp\/v2\/tags?post=6956"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}