{"id":12827,"date":"2024-07-23T12:00:35","date_gmt":"2024-07-23T10:00:35","guid":{"rendered":"https:\/\/fgu.antstudio.dev\/udalost\/lecture-3\/"},"modified":"2024-09-17T09:56:37","modified_gmt":"2024-09-17T07:56:37","slug":"lecture-3","status":"publish","type":"udalost","link":"https:\/\/fgu.cas.cz\/en\/event\/lecture-3\/","title":{"rendered":"Lecture &#8220;Neutral lipid hydrolases in the spotlight of metabolism&#8221;"},"content":{"rendered":"<p>Adipocytes within adipose tissue play a key role in controlling energy homeostasis. During overnutrition, adipocytes store energy as triacylglycerol (TG) in cytosolic lipid droplets. Upon energy need, TGs are mobilized by hydrolases in a process termed lipolysis to supply the body with fatty acids for fuel, signaling molecules, and building blocks for cellular membranes. The two enzymes accounting for more than 90% of adipocyte TG hydrolase activity are adipose triglyceride lipase (ATGL) and hormone-sensitive lipase (HSL). How the loss of both lipases affects brown and white adipose tissue physiology upon metabolic stress like cold and aging will be discussed in this seminar.<\/p>\n<p><strong>IPHYS contact person:<\/strong> Ond\u0159ej Kuda, ondrej.kuda@fgu.cas.cz<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Prof. Renate Schreiber, University of Graz<\/p>\n","protected":false},"author":5,"featured_media":55280,"template":"","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"kategorie-udalosti":[84],"class_list":["post-12827","udalost","type-udalost","status-publish","has-post-thumbnail","hentry","kategorie-udalosti-lectures"],"acf":[],"_links":{"self":[{"href":"https:\/\/fgu.cas.cz\/en\/wp-json\/wp\/v2\/udalost\/12827","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/fgu.cas.cz\/en\/wp-json\/wp\/v2\/udalost"}],"about":[{"href":"https:\/\/fgu.cas.cz\/en\/wp-json\/wp\/v2\/types\/udalost"}],"author":[{"embeddable":true,"href":"https:\/\/fgu.cas.cz\/en\/wp-json\/wp\/v2\/users\/5"}],"version-history":[{"count":0,"href":"https:\/\/fgu.cas.cz\/en\/wp-json\/wp\/v2\/udalost\/12827\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/fgu.cas.cz\/en\/wp-json\/wp\/v2\/media\/55280"}],"wp:attachment":[{"href":"https:\/\/fgu.cas.cz\/en\/wp-json\/wp\/v2\/media?parent=12827"}],"wp:term":[{"taxonomy":"kategorie-udalosti","embeddable":true,"href":"https:\/\/fgu.cas.cz\/en\/wp-json\/wp\/v2\/kategorie-udalosti?post=12827"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}