{"id":30194,"date":"2025-09-10T15:06:52","date_gmt":"2025-09-10T13:06:52","guid":{"rendered":"https:\/\/fgu.antstudio.dev\/?post_type=vyzkumny-projekt&#038;p=30194"},"modified":"2025-09-11T09:16:44","modified_gmt":"2025-09-11T07:16:44","slug":"chillies-can-reduce-the-pain","status":"publish","type":"vyzkumny-projekt","link":"https:\/\/fgu.cas.cz\/en\/research-project\/chillies-can-reduce-the-pain\/","title":{"rendered":"Chillies can reduce the pain"},"content":{"rendered":"<p><strong>TRPV1 antagonist attenuates postoperative hypersensitivity by central and peripheral mechanisms. Such a finding was reached by the scientists from the department of Functional Morphology who studied the\u00a0mechanisms of chronic pain syndromes and their treatment options.<\/strong><\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p><strong>A<\/strong>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<strong>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 B\u00a0\u00a0\u00a0<\/strong>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<strong>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0C<\/strong><br \/>\n<img fetchpriority=\"high\" decoding=\"async\" class=\"size-full wp-image-26728 aligncenter\" src=\"https:\/\/fgu.cas.cz\/wp-content\/uploads\/2024\/08\/shot-240823-125356.png\" alt=\"-\" width=\"959\" height=\"324\" title=\"\" srcset=\"https:\/\/fgu.cas.cz\/wp-content\/uploads\/2024\/08\/shot-240823-125356.png 959w, https:\/\/fgu.cas.cz\/wp-content\/uploads\/2024\/08\/shot-240823-125356-300x101.png 300w, https:\/\/fgu.cas.cz\/wp-content\/uploads\/2024\/08\/shot-240823-125356-768x259.png 768w\" sizes=\"(max-width: 959px) 100vw, 959px\" \/><\/p>\n<p><strong>(A) <\/strong>Kapsaicin &#8211; aktiv\u00e1tor TRPV1 receptor\u016f je obsa\u017een v&nbsp;p\u00e1liv\u00fdch papri\u010dk\u00e1ch. <strong>(B) <\/strong>Imunohistochemick\u00e9 barven\u00ed spin\u00e1ln\u00edch gangli\u00ed (\u010derven\u011b) ukazuje p\u0159\u00edtomnost TRPV1 receptor\u016f v\u00a0mal\u00fdch neuronech. <strong>(C) <\/strong>Incize vede k\u00a0v\u00fdrazn\u00e9mu zv\u00fd\u0161en\u00ed citlivosti na tepeln\u00e9 podn\u011bty (modr\u00e9 troj\u00faheln\u00ed\u010dky). Intrathek\u00e1ln\u00ed pod\u00e1n\u00ed blok\u00e1toru TRPV1 receptor\u016f vede k\u00a0v\u00fdrazn\u00e9mu sn\u00ed\u017een\u00ed t\u00e9to citlivosti (\u010derven\u00e1 kole\u010dka).<\/p>\n<p>Uchytilov\u00e1, Eva &#8211; \u0160picarov\u00e1, Diana &#8211; Pale\u010dek, Ji\u0159\u00ed<\/p>\n<p>TRPV1 antagonist attenuates postoperative hypersensitivity by central and peripheral mechanisms. Molecular Pain. Ro\u010d. 10, \u010d. 2014 (2014), s. 67<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>TRPV1 antagonist attenuates postoperative hypersensitivity by central and peripheral mechanisms. Such a finding was reached by the scientists from the department of Functional Morphology who studied the\u00a0mechanisms of chronic pain syndromes and their treatment options. &nbsp; &nbsp; A\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 B\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0C (A) Kapsaicin &#8211; aktiv\u00e1tor TRPV1 receptor\u016f je obsa\u017een v&nbsp;p\u00e1liv\u00fdch papri\u010dk\u00e1ch. (B) Imunohistochemick\u00e9 barven\u00ed spin\u00e1ln\u00edch gangli\u00ed (\u010derven\u011b) [&hellip;]<\/p>\n","protected":false},"author":1,"template":"","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"oddeleni":[185],"poskytovatel":[],"stav-projektu":[209],"class_list":["post-30194","vyzkumny-projekt","type-vyzkumny-projekt","status-publish","hentry","oddeleni-pain-research","stav-projektu-current-projects"],"acf":[],"_links":{"self":[{"href":"https:\/\/fgu.cas.cz\/en\/wp-json\/wp\/v2\/vyzkumny-projekt\/30194","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/fgu.cas.cz\/en\/wp-json\/wp\/v2\/vyzkumny-projekt"}],"about":[{"href":"https:\/\/fgu.cas.cz\/en\/wp-json\/wp\/v2\/types\/vyzkumny-projekt"}],"author":[{"embeddable":true,"href":"https:\/\/fgu.cas.cz\/en\/wp-json\/wp\/v2\/users\/1"}],"version-history":[{"count":0,"href":"https:\/\/fgu.cas.cz\/en\/wp-json\/wp\/v2\/vyzkumny-projekt\/30194\/revisions"}],"wp:attachment":[{"href":"https:\/\/fgu.cas.cz\/en\/wp-json\/wp\/v2\/media?parent=30194"}],"wp:term":[{"taxonomy":"oddeleni","embeddable":true,"href":"https:\/\/fgu.cas.cz\/en\/wp-json\/wp\/v2\/oddeleni?post=30194"},{"taxonomy":"poskytovatel","embeddable":true,"href":"https:\/\/fgu.cas.cz\/en\/wp-json\/wp\/v2\/poskytovatel?post=30194"},{"taxonomy":"stav-projektu","embeddable":true,"href":"https:\/\/fgu.cas.cz\/en\/wp-json\/wp\/v2\/stav-projektu?post=30194"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}