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Biogenesis and regulation of mitochondrial oxidative phosphorylation apparatus

In our laboratory we study mitochondrial complexes involved in the cellular ATP provision. We are interested in the assembly of those multisubunit protein complexes, detailed aspects of their molecular function and how the cell/organism adapts their dysfunction. In addition to basic research in this area we also have clinical collaborations on inborn mitochondrial disorders and on heart failure. Currently, we can offer projects focussed on ATP synthase and cytochrome c oxidase.