News
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Ivo Syrový has died
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Helena Janíčková received a prestigious ERC CZ grant
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Implants - yes, but only for health reasons
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Obesity - a serious contemporary problem
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Replacement vessels from the umbilical cord
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Science Fair attracted nearly 60 thousand science fans
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170 000 views of the interview with Lucie Bačáková. Topic? Implants!
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How to train memory?
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Ondřej Kuda a Marcela Křížová zaujali přednáškou "Mateřské mléko - bílé zlato"
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Invitation to the lecture " Maternal Milk - White Gold"
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Do not forget about Alzheimer's disease
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70 years of the Institute of Physiology of the CAS
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Brain Week begins!
Events calendar
- planned
- past
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2.9.
15:00 -
9.9.
15:00Lecture
Laboratory of Bioenergetics, IPHYS
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16.9.
15:00Lecture
Laboratory of Neurochemistry, IPHYS
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23.9.
15:00Lecture "Neutral lipid hydrolases in the spotlight of metabolism"
Renate Schreiber, Institute of Molecular Biosciences, University of Graz, Graz, Austria
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30.9.
15:00 -
7.10.
15:00 -
14.10.
15:00Lecture
Laboratory of Membrane Transport, IPHYS
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21.10.
15:00Lecture
Laboratory of Adipose Tissue Biology, IPHYS
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20.11.
17:00Přednáška "Prostorová paměť u Alzheimerovy nemoci: od výzkumu k pacientům"
Přednáší: RNDr. Jan Svoboda, Ph.D. (FGÚ AV ČR) a Prof. MUDr. Jan Laczó, Ph.D. (Neurologická klinika 2.LF UK a FN Motol)
v rámci cyklu přednášek "Lidské tělo ve zdraví i nemoci"
AV ČR, Národní 3, Praha 1
Publications
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Clock in the choroid plexus in the brain are sensitive to disruption of the daily regime but resistant to inflammatory conditions
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The ability to transport K+ cations and hence the physiological role of Na+/H+ antiporters is influenced by the composition of their hydrophilic C-termini
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A new method for quantification of information transmission reliability between neurons
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How does 14-3-3 protein block CaMKK protein kinase activity?
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Risk factors for cardiovascular and metabolic diseases are associated with misaligned sleep schedules
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How do the cells gain enough potassium?
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Heat from skeletal muscle can protect not only against cold but also against obesity
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Take a pill in the morning or in the evening? The mood stabilizer lithium affects the brain differently depending on the time of day
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Heat or cold? New insights into the functioning of temperature-sensitive ion channels obtained in collaboration with Lund University
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Unravelling novel regulatory mechanisms in the human Na+/H+ antiporter NHA2
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Characterization of novel antidiabetic drug with less side effects on bone metabolism
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The structure of steroids fundamentally affects their effect at the N-methyl-D-aspartate receptors
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Ion channel TRPC5 as a target for treating neuropathic pain
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New lipid classes in human breastmilk
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Maternal rhythmic behavior supports the development of the fetal biological clock
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New findings on the structure of the FOXO4: p53 complex - a key factor in senescence regulation
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Metabolomics atlas of a mouse
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The effectivity of opioid analgesics is reduced by CCL2 chemokine
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Gliflozins - more than just antidiabetics
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Targeted modulation of NMDA receptors is a key for the effective treatment of neurological and neurodevelopmental diseases
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Structural basis of heat-induced opening of TRP channels
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New findings may help to improve diagnostic methods for breast cancer
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Palmitoylation controls NMDA receptor susceptibility to neurosteroids
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Clove oil alleviates cold-induced toothache by blocking the TRPC5 ion channel
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Nanocellulose as a promising cell carrier for applications in regenerative medicine
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Antidiabetic lipid mediators as neutral lipase substrates
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Mitochondrial cardiolipin in adipose tissue as a novel target for treatment of cardiac cachexia
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Neurosteroid pregnenolone sulfate - revealing of its site of action at the N-methyl-D-aspartate receptor
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Dietary supplementation with Krill oil as a novel strategy to improve insulin sensitivity and reduce liver fat accumulation in obesity
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Novel mechanism of insulin secretion highlights the importance of redox signalization
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Losartan attenuates neuroinflammation and neuropathic pain in paclitaxel-induced peripheral neuropathy
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Signalling bias as the way to side-effect-free medication
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Lipokine 5-PAHSA is Regulated by Adipose Triglyceride Lipase and Primes Adipocytes for de novo Lipogenesis in Mice
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Elucidation of TRPA1 activation mechanisms may help to understand the pathophysiology of chronic pain
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Innovative method of the Forhkead transcription factor FOXO3 regulation
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Transcription factor Hif-1a is required for the correct development of the sympathetic nervous system and innervation of the heart
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The resistance of pancreatic beta cells to oxidative stress, which accompanies diabetes type 2, can be increased by mitochondria-targeted antioxidants
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A promising pharmacological approach in cardiovascular disease prevention
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Small amounts of inorganic nitrate or beetroot provide substantial protection from salt-induced Increases in blood pressure
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The effect of gut microbiome on expression of genes involved in regulation of stress response in chronic stress