Annotation: The regeneration of tissues lost due to accidents, tumor removal, or aging is a critical issue in modern medicine. Recently, tissue engineering has involved combining disease therapy with tissue regeneration using advanced functional biomaterials. Composite scaffolds containing bioactive glass nanoparticles are promising candidates for this purpose. These nanoparticles can be doped with therapeutic ions, such as cerium, that have anticancer, antioxidant, and antibacterial properties. Incorporating bioactive glass nanoparticles into a biocompatible polymer while preparing the scaffolds is expected to enhance bioactivity, mechanical strength, and appropriate biodegradation. Additionally, the scaffolds can be functionalized with antibacterial and/or anticancer drugs. These scaffolds are expected to regenerate bone tissue due to their osteoconductivity (adhesion and growth of bone cells), osteoinductivity (osteogenic differentiation of stem cells), and angiogenic potential.

IPHYS contact person: Lucie Bačáková, Laboratory of Biomaterials and Tissue Engineering, lucie.bacakova@fgu.cas.cz