Cutting-edge science for health


Institute of Physiology registered the greatest interest of the applications for the internships. One-fifth of the all applications were sent there! 184 students, who sent in total 354 applications, were interested in internships at the Institute. Within the Open Science at the IPHYS, fiinally 8 internships for 16 selected students will be realized. Students were most interested in the topic "Epilepsy as a metabolic disease" supervised by Jakub Otáhal and also the topic supervised by Michaela Tencerová "How hard are the bones and what is hidden under them?". 31 institutes of the Czech Academy of Sciences participated in the whole project, 85 lecturers will lead 103 internships for 196 students. More about the Open Science project.

Tomáš Čajka is a co-author of the unique software for analyses of complex lipids in biological samples (15.1. 2021)

Processing of instrumental files acquired during untargeted metabolomics and lipidomics analyses represents a challenging task. It is estimated that only 20 percent of signals (features) collected during untargeted liquid chromatography–mass spectrometry (LC–MS) methods can be annotated. MS-DIAL represents user-friendly, open-access software for processing untargeted metabolomics and lipidomics instrumental files. The latest version contains an atlas (database) for 117 lipid subclasses with predicted retention times, tandem mass spectrometry spectra (MS/MS), and collision cross sections (CCS) for annotation of complex lipids in biological samples. Using MS-DIAL 4, a higher number of annotated complex lipids in biological samples is achieved compared to other software programs in this field permitting more meaningful data interpretation.

H. Tsugawa, K. Ikeda, M. Takahashi, A. Satoh, Y. Mori, H. Uchino, N. Okahashi, Y. Yamada, I. Tada, P. Bonini, Y. Higashi, Y. Okazaki, Z. Zhou, Z.-J. Zhu, J. Koelmel, T. Cajka, O. Fiehn, K. Saito, M. Arita, M. Arita: A lipidome atlas in MS-DIAL 4. Nature Biotechnology 38 (2020) 1159–1163. IF = 36.558 DOI

The Best IPHYS Publication Awards (16.12. 2020)

On 15 December 2020, the winners of the Best Publication Awards for 2019  were announced.

The Award for the Best Publication by IPHYS Authors for 2019 went to Dr. Jan Neckář for the publication

Neckář J, Md Hye Khan A, Gross GJ, Cyprová M, Hrdlička J, Kvasilová A, Falck JR,  Campbell WB, Sedláková L, Škutová Š, Olejníčková V, Gregorovičová M, Sedmera D, Kolář F, Imig JD: Epoxyeicosatrienoic acid analog EET-B attenuates post-myocardial infarction remodeling in spontaneously hypertensive rats. Clinical Science. 2019, roč. 133, s. 936-951. IF: 5,223 DOI

The Pavel Flachs Award for the Best Publication by IPHYS Authors with a Corresponding Author under the Age of 35 for 2019 went to Dr. Markéta Zikmundová (née Bačáková) and Júlia Pajorová for the publication

Bačáková M, Pajorová J, Brož A, Hadraba D, Lopot F, Zavaďáková A, Vištejnová L, Beňo M, Kostič I, Jenčová V, Bačáková L: A two-layer skin construct consisting of a collagen hydrogel reinforced by a fibrin-coated polylactide nanofibrous membrane. International Journal of Nanomedicine. 2019, roč. 14, s. 5033-5050. IF: 5,115 DOI

The Award for the Best Review by Young Researchers published in Physiological Research in 2020 was presented to three different authors: Kristýna Čuňátová, Eliška Koňaříková, and Sofia Moraresku.  

Congratulations to all the winners!

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