Cutting-edge science for health


Memory Park´s psychological tests attracted over 1200 people (24.3. 2021)

Vybrané psychologické testy, které FGÚ zpřístupnilo, jako součást letošního online Týdne mozku měly úspěch. Během týdenní akce si jeden z testů zkusilo udělat 1261 lidí, alespoň jeden test dokončilo 1023 lidí a alespoň jeden dotazník vyplnilo 864 lidí (úplná statistika testů). Zájemci si mohli vyzkoušet test pracovní a epizodické paměti, test převzetí perspektivy nebo test skrytého cíle. Testy jsou používané ke zjištění postižení paměti a prostorové orientace u pacientů s Alzheimerovou chorobou, epilepsií nebo schizofrenií. Testy je i nadále možné vyzkoušet na tomto odkazu.

Institute of Physiology registered the greatest interest of the applications for the internships. One-fifth of the all applications were sent there! 184 students, who sent in total 354 applications, were interested in internships at the Institute. Within the Open Science at the IPHYS, fiinally 8 internships for 16 selected students will be realized. Students were most interested in the topic "Epilepsy as a metabolic disease" supervised by Jakub Otáhal and also the topic supervised by Michaela Tencerová "How hard are the bones and what is hidden under them?". 31 institutes of the Czech Academy of Sciences participated in the whole project, 85 lecturers will lead 103 internships for 196 students. More about the Open Science project.

Tomáš Čajka is a co-author of the unique software for analyses of complex lipids in biological samples (15.1. 2021)

Processing of instrumental files acquired during untargeted metabolomics and lipidomics analyses represents a challenging task. It is estimated that only 20 percent of signals (features) collected during untargeted liquid chromatography–mass spectrometry (LC–MS) methods can be annotated. MS-DIAL represents user-friendly, open-access software for processing untargeted metabolomics and lipidomics instrumental files. The latest version contains an atlas (database) for 117 lipid subclasses with predicted retention times, tandem mass spectrometry spectra (MS/MS), and collision cross sections (CCS) for annotation of complex lipids in biological samples. Using MS-DIAL 4, a higher number of annotated complex lipids in biological samples is achieved compared to other software programs in this field permitting more meaningful data interpretation.

H. Tsugawa, K. Ikeda, M. Takahashi, A. Satoh, Y. Mori, H. Uchino, N. Okahashi, Y. Yamada, I. Tada, P. Bonini, Y. Higashi, Y. Okazaki, Z. Zhou, Z.-J. Zhu, J. Koelmel, T. Cajka, O. Fiehn, K. Saito, M. Arita, M. Arita: A lipidome atlas in MS-DIAL 4. Nature Biotechnology 38 (2020) 1159–1163. IF = 36.558 DOI

The Best IPHYS Publication Awards (16.12. 2020)

On 15 December 2020, the winners of the Best Publication Awards for 2019  were announced.

The Award for the Best Publication by IPHYS Authors for 2019 went to Dr. Jan Neckář for the publication

Neckář J, Md Hye Khan A, Gross GJ, Cyprová M, Hrdlička J, Kvasilová A, Falck JR,  Campbell WB, Sedláková L, Škutová Š, Olejníčková V, Gregorovičová M, Sedmera D, Kolář F, Imig JD: Epoxyeicosatrienoic acid analog EET-B attenuates post-myocardial infarction remodeling in spontaneously hypertensive rats. Clinical Science. 2019, roč. 133, s. 936-951. IF: 5,223 DOI

The Pavel Flachs Award for the Best Publication by IPHYS Authors with a Corresponding Author under the Age of 35 for 2019 went to Dr. Markéta Zikmundová (née Bačáková) and Júlia Pajorová for the publication

Bačáková M, Pajorová J, Brož A, Hadraba D, Lopot F, Zavaďáková A, Vištejnová L, Beňo M, Kostič I, Jenčová V, Bačáková L: A two-layer skin construct consisting of a collagen hydrogel reinforced by a fibrin-coated polylactide nanofibrous membrane. International Journal of Nanomedicine. 2019, roč. 14, s. 5033-5050. IF: 5,115 DOI

The Award for the Best Review by Young Researchers published in Physiological Research in 2020 was presented to three different authors: Kristýna Čuňátová, Eliška Koňaříková, and Sofia Moraresku.  

Congratulations to all the winners!

Pavel Mareš received the Medal of the Czech Medical Association (26.10. 2020)

On 13 October 2020, Dr. Pavel Mareš received the Gold Commemorative Medal of the Czech Medical Society of Jan Evangelista Purkyně for exceptional achievements in his scientific career and active participation in professional associations. Congratulations!


Eva Zažímalová visited the Institute of Physiology (22.9. 2020)

On 16 September 2020, the Institute of Physiology welcomed Dr. Eva Zažímalová, the President of the Czech Academy of Sciences, during her tour of institutional on-site visits. Together with her team, she visited several research laboratories and service departments. She also inspected the ongoing reconstruction of the animal facility. More


Michaela Tencerová obtained the prestigious grant (31.8. 2020)

Dr. Michaela Tencerová, the Head of the Laboratory of Molecular Physiology of Bone, received a five-year grant from the EFSD / Novo Nordisk Foundation Future Leaders Award Programme. The project is focused on the research of bone marrow adipose tissue and its metabolic activity in obesity and diabetes. Increased accumulation of bone marrow adipose tissue is associated with a high risk of bone fractures and the development of osteoporosis in obese and diabetic patients. This project may lead to an alternative approach in the prevention and treatment of bone fragility in patients with metabolic complications. Congratulations!

MediAim – New Therapeutic and Drug Development Strategies (23.6. 2020)

To understand the essence of diseases of affluence and improve their treatment. Such is the goal of the MediAim consortium, which brings together three centers of excellence in science, research, and clinical practice. The Institute for Clinical and Experimental Medicine (IKEM) and two institutes of the Czech Academy of Sciences – the Institute of the Organic Chemistry and Biochemistry (IOCB) and the Institute of Physiology (IPHYS) – have joined forces to seek out new strategies for treating cardiovascular, viral, neurodegenerative, and oncologic diseases as well as diabetes and obesity.  More information:

Press release 


90´ ČT24 (24.6.2020) topic: Treatment of a civilization diseases

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