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SUMMER COURSE FOR MEDICAL STUDENTS 2021 (30.6. 2021)

The one-week summer course on Advances in Selected Areas of Biomedicine for Students of Medical Faculties will be held in September 6-10, 2021.

The course will focus on acquiring new knowledge and practical experience with biomedical research. The aim is to increase the qualification of graduates of medical faculties of the Charles University in Prague in the field of biomedical research and to increase their interest in postgraduate education.The course is primarily, but not exclusively, intended for 1st and 2nd year students, it will be in English and its capacity is limited to 20 participants. Deadline for application is July 302021. Applicants will be selected on a first come, first-serve basis. The course is free of charge. APPLICATION

MIchaela Tencerová uspěla v soutěži L'Oréal-UNESCO Pro ženy ve vědě (28.6. 2021)

Projekt L'Oréal-UNESCO Pro ženy ve vědě byl založen v Paříži v roce 1998. Cílí na vědkyně do 40 let, přičemž v Česku projekt začal v roce 2006. Do tuzemské verze mezinárodního programu se letos přihlásilo 66 vědkyň. Porota složená ze zástupců Akademie věd ČR, UNESCO a L'Oréal vybrala 13 semifinalistek. Laureátkami se nakonec staly neuroložka Petra Laššuthová, rostlinná genetička Terezie Mandáková a fyzioložka Michaela Tencerová.

Michaela Tencerová zkoumá metabolické změny v kostní dřeni, což by mohlo pomoci ke zlepšení léčby osteoporózy neboli řídnutí kostí. Tato nemoc podle Tencerové nejvíce ohrožuje pacienty trpící metabolickým onemocněním - například cukrovkou či obezitou, a především ženy. „Naše nedávná zjištění ukázala, že lámavost kostí v obezitě způsobuje akumulace tukové tkáně v kostní dřeni, která vede k urychlenému stárnutí a vyčerpání jejích kmenových buněk, což zhoršuje vytváření zdravé kostní hmoty,“ uvedla vědkyně. „Hlavním cílem naší studie je proto zkoumat funkční význam metabolických změn v kostní dřeni a zjistit, zda jim lze zabránit pomocí dietních opatření nebo farmakologicky, tedy použitím léků pro léčbu metabolických onemocnění,“ uzavřela. Poznatky by podle ní mohly pomoci nejen k cílenější léčbě, ale třeba i zamezit propuknutí nemoci. Gratulujeme!

Jakub Otáhal was appointed a Professor (10.5. 2021)

Assoc. Prof. MUDr.  Jakub Otáhal, PhD was appointed a Professor in Medical Physiology and Pathophysiology. Czech president signed a letter of appointment on May 8, 2021. The appointment procedure took a place at Charles University, Prague.

7 scientists from the Institute of Physiology are among the 2% most cited scientists in the world (10.5. 2021)

Elsevier, SciTech Strategies and John P. A. Ioannidis from University of Standford prepared a list of  2 % of the most cited scientists from all fieldswhich includes the Scopus database for 2019. A total of 359 of them work at Czech research institutions (107 of them are from the Czech Academy of Sciences). The list includes 7 current and former scientists from the Institute of Physiology CAS: Petr Ježek, Stanislav Tuček, Pavel Mareš, Tomáš Čajka, Ivan Mikšík, Lucie Bačáková and Jiří Vaněček. More

Petr Lánský has died (28.4. 2021)

With deep sorrow we announce that on April 24, 2021 died at the age of 72 doc. RNDr. Petr Lánský, DrSc., Senior researcher at the Institute of Physiology of the Czech Academy of Sciences and founder of the field of computational neuroscience in the Czech Republic.

Memory Park´s psychological tests attracted over 1200 people (24.3. 2021)

Psychological tests which were a part of online Brain Awareness Week 2021, had a success. During the weekly event, 1261 people tried to take one of the tests, 1023 people completed at least one test and 864 people completed at least one questionnaire (complete statistics). The tests are used to detect memory impairment and space orientation of patients with Alzheimer's disease, epilepsy or schizophrenia. Tests are still available at this link.

Institute of Physiology registered the greatest interest of the applications for the internships. One-fifth of the all applications were sent there! 184 students, who sent in total 354 applications, were interested in internships at the Institute. Within the Open Science at the IPHYS, fiinally 8 internships for 16 selected students will be realized. Students were most interested in the topic "Epilepsy as a metabolic disease" supervised by Jakub Otáhal and also the topic supervised by Michaela Tencerová "How hard are the bones and what is hidden under them?". 31 institutes of the Czech Academy of Sciences participated in the whole project, 85 lecturers will lead 103 internships for 196 students. More about the Open Science project.

Tomáš Čajka is a co-author of the unique software for analyses of complex lipids in biological samples (15.1. 2021)

Processing of instrumental files acquired during untargeted metabolomics and lipidomics analyses represents a challenging task. It is estimated that only 20 percent of signals (features) collected during untargeted liquid chromatography–mass spectrometry (LC–MS) methods can be annotated. MS-DIAL represents user-friendly, open-access software for processing untargeted metabolomics and lipidomics instrumental files. The latest version contains an atlas (database) for 117 lipid subclasses with predicted retention times, tandem mass spectrometry spectra (MS/MS), and collision cross sections (CCS) for annotation of complex lipids in biological samples. Using MS-DIAL 4, a higher number of annotated complex lipids in biological samples is achieved compared to other software programs in this field permitting more meaningful data interpretation.

H. Tsugawa, K. Ikeda, M. Takahashi, A. Satoh, Y. Mori, H. Uchino, N. Okahashi, Y. Yamada, I. Tada, P. Bonini, Y. Higashi, Y. Okazaki, Z. Zhou, Z.-J. Zhu, J. Koelmel, T. Cajka, O. Fiehn, K. Saito, M. Arita, M. Arita: A lipidome atlas in MS-DIAL 4. Nature Biotechnology 38 (2020) 1159–1163. IF = 36.558 DOI

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