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Tomáš Čajka is a co-author of the unique software for analyses of complex lipids in biological samples (15.1. 2021)

Processing of instrumental files acquired during untargeted metabolomics and lipidomics analyses represents a challenging task. It is estimated that only 20 percent of signals (features) collected during untargeted liquid chromatography–mass spectrometry (LC–MS) methods can be annotated. MS-DIAL represents user-friendly, open-access software for processing untargeted metabolomics and lipidomics instrumental files. The latest version contains an atlas (database) for 117 lipid subclasses with predicted retention times, tandem mass spectrometry spectra (MS/MS), and collision cross sections (CCS) for annotation of complex lipids in biological samples. Using MS-DIAL 4, a higher number of annotated complex lipids in biological samples is achieved compared to other software programs in this field permitting more meaningful data interpretation.

H. Tsugawa, K. Ikeda, M. Takahashi, A. Satoh, Y. Mori, H. Uchino, N. Okahashi, Y. Yamada, I. Tada, P. Bonini, Y. Higashi, Y. Okazaki, Z. Zhou, Z.-J. Zhu, J. Koelmel, T. Cajka, O. Fiehn, K. Saito, M. Arita, M. Arita: A lipidome atlas in MS-DIAL 4. Nature Biotechnology 38 (2020) 1159–1163. IF = 36.558 DOI

Competition for the best IPHYS publication (16.12. 2020)

V úterý 15. prosince byly vyhlášeny výsledky Soutěže o nejlepší publikace s autory z FGÚ za rok 2019. 

Cenu v Soutěži o nejlepší publikace s autory z FGÚ za rok 2019 získal RNDr. Jan Neckář, Ph.D. za publikaci:

Neckář J, Md Hye Khan A, Gross GJ, Cyprová M, Hrdlička J, Kvasilová A, Falck JR,  Campbell WB, Sedláková L, Škutová Š, Olejníčková V, Gregorovičová M, Sedmera D, Kolář F, Imig JD: Epoxyeicosatrienoic acid analog EET-B attenuates post-myocardial infarction remodeling in spontaneously hypertensive rats. Clinical Science. 2019, roč. 133, s. 936-951. IF: 5,223 DOI

Cenu Pavla Flachse za nejlepší publikaci s autory z FGÚ za rok 2019 s korespondujícím autorem do 35 let získala Ing. Markéta Zikmundová (Bačáková), Ph.D. a Mgr. Júlia Pajorová za publikaci:

Bačáková M, Pajorová J, Brož A, Hadraba D, Lopot F, Zavaďáková A, Vištejnová L, Beňo M, Kostič I, Jenčová V, Bačáková L: A two-layer skin construct consisting of a collagen hydrogel reinforced by a fibrin-coated polylactide nanofibrous membrane. International Journal of Nanomedicine. 2019, roč. 14, s. 5033-5050. IF: 5,115 DOI

Zároveň proběhlo vyhlášení výsledků Soutěže mladých vědeckých pracovníků o nejlepší review ve Physiological Research za rok 2020. Bylo uděleno 3 x 2. místo, které získaly: Mgr. Kristýna Čunátová, Ing. Mgr. Eliška Koňaříková a Sofia Moraresku, MSc.

Všem oceněným gratulujeme!

Pavel Mareš awarded medal of the Czech Medical Association (26.10. 2020)

Prof. MUDr. Pavel Mareš, DrSc. obdržel 13. 10. 2020 Zlatou pamětní medaili České lékařské společnosti Jana Evangelisty Purkyně za výjimečné úspěchy ve vědecké kariéře a aktivní práci v odborných společnostech. Gratulujeme!

 

Eva Zažímalová visited Institute of Physiology CAS (22.9. 2020)

V úterý 15. září si předsedkyně Akademie věd ČR Eva Zažímalová v rámci série návštěv pracovišť prohlédla Fyziologický ústav. Společně se svým doprovodem navštívila několik vědeckých i servisních oddělení a prohlédla si také pokračující přestavbu zvěřince. Více

 

Michaela Tencerová gained the prestigious grant (31.8. 2020)

Mgr. Michaela Tencerová, PhD., vedoucí laboratoře Molekulární fyziologie kosti, získala pětiletý grant od EFSD/Novo Nordisk Foundation, v rámci Future Leaders Award Programme. Projekt je zaměřen na výzkum tukové tkáně kostní dřeně a její metabolické aktivity při obezitě a diabetu. Zvýšená akumulace tukové tkáně kostní dřeně je spojená s vysokým rizikem zlomenin kostí a rozvojem osteoporózy u obézních a diabetických pacientů. Tento projekt může vést k alternativnímu přístupu v prevenci a léčbě lámavosti kostí u pacientů s metabolickými komplikacemi. Gratulujeme.

 

MediAim – New Therapeutic and Drug Development Strategies (23.6. 2020)

To understand the essence of diseases of affluence and improve their treatment. Such is the goal of the MediAim consortium, which brings together three centers of excellence in science, research, and clinical practice. The Institute for Clinical and Experimental Medicine (IKEM) and two institutes of the Czech Academy of Sciences – the Institute of the Organic Chemistry and Biochemistry (IOCB) and the Institute of Physiology (IPHYS) – have joined forces to seek out new strategies for treating cardiovascular, viral, neurodegenerative, and oncologic diseases as well as diabetes and obesity.  More information: www.mediaim.cz.

Press release 

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90´ ČT24 (24.6.2020) topic: Treatment of a civilization diseases

Zdeněk Drahota and Alena Sumová Awarded Honorary Medals of the Czech Academy of Sciences (3.2. 2020)

On 29 January 2020, two prominent scientists from the Institute of Physiology, Zdeněk Drahota and Alena Sumová, received honorary medals awarded by the Czech Academy of Sciences from the hands of the President of the CAS, Eva Zažímalová.

Zdeněk Drahota received the Jan Evangelista Purkyně Honorary Medal for Merit in the Biomedical Sciences. Zdeněk Drahota significantly contributed to the development of the study of animal metabolism with a focus on the processes of energy conversion in the cell. Highly respected in the international biochemical community, his research into the basic mechanisms of mitochondrial energy function laid the foundation for the development of the study of mammalian bioenergetics. Knowledge of the structure, function, and biogenesis of mitochondria has become one of the main and highly successful research directions of the Institute. It has led to the establishment of several new laboratories, which carry out first-rate research into mitochondrial issues, from molecular structure to translational aspects of metabolic disorders.

Alena Sumová received the Vojtěch Náprstek Honorary Medal for Merit in Science Popularisation. Her research focuses on the study of biological clocks and time systems in mammals, including humans, which affect both physical and mental abilities and the overall setting of the organism. The primary goal of Alena Sumová and her group is to understand the impact of disruption of time regulation on human health during early development, in adulthood, and at old age. Alena Sumová often discusses this topic in the media; she gives interviews and commentaries on television and radio. She also works as a teacher, conducting seminars at universities and developing programmes for secondary schools. More

  

  

Martin Zápotocký Elected the Vice-president of the Organization for Computational Neurosciences (16.1. 2020)

Martin Zápotocký became the Vice-President of the Organization for Computational Neurosciences. on January 1, 2020. The organization has more than 2000 members from around the world and organizes annual conferences with 500-600 participants. The 2015 conference was held in Prague under the co-hosting of the Institute of Physiology.

Ladislav Vyklický Awarded the Prize of the Minister of Health (8.1. 2020)

Ladislav Vyklický received the 2019 Prize of the Minister of Health for Medical Research and Development on December 17, 2019. The Minister awards the prize for extraordinary results achieved within specific grants or institutional support in research and development provided by the Ministry of Health. Ladislav Vyklický was recognized for his project “Genetic and functional study of NMDA receptors focused on possible diagnosis and treatment of schizophrenia”. The co-researchers are Aleš Balík (Institute of Physiology);  Jiří Horáček (National Institute of Mental Health); and Eva Kudová (Institute of Organic Chemistry and Biochemistry). Full report 

 

Vojtěch Kumpošt Awarded the Prize of the Ministry of Education, Youth and Sports (5.12. 2019)

Vojtěch Kumpošt, who worked at the Laboratory of Developmental Epileptology of the Institute of Physiology since his bachelor studies, was awarded the 2019 Prize of the Ministry of Education, Youth and Sports in Higher Education, Science, and Research in the category of Master Studies. He received the prize from the hands of Minister Robert Plaga for achieving results that contributed to discoveries in research into the mechanisms of epileptic seizures and were published in the prestigious journal Nature Neuroscience. Vojtěch Kumpošt was a student of the Faculty of Electrical Engineering of the Czech Technical University; now he works at the Karlsruhe Institute of Technology in Germany.

 

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