The role of synaptic transmission modulation in pain

Pain: Pain is an unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described by the terms of such damage. Nociception: The process of detecting and signalling the presence of a painful stimulus in the peripheral and central nervous system.

MEANING OF DORSAL HORN OF SPINAL CORD IN NOCICEPTIVE TRANSMISSION

MEANING OF PAIN

ACUTE PAIN Important signalling mechanism x PATHOLOGICAL PAIN Chronic (e.g. neuropathic) pain