Obesity, high blood sugar or insulin resistance are among the most common symptoms of metabolic syndrome. However, its hereditary causes are not yet fully understood. Scientists from the Laboratory of Bioenergetics of the Institute of Physiology of the CAS and the National Institute CarDia have found that DNA variability in mitochondria could play an important role in the development of metabolic syndrome symptoms.
Reference: Pecina P., Čunátová K., Kaplanová V., Puertas-Frias G., Šilhavý J., Tauchmannová K., Vrbacký M., Čajka T., Gahura O., Hlaváčková M., Stránecký V., Kmoch S., Pravenec M., Houštěk J., Mráček T., Pecinová A.: Haplotype variability in mitochondrial rRNA predisposes to metabolic syndrome. Communications Biology 7(1):1116 (2024). DOI
